Publications by authors named "Mihaela Farkas"
Aims: Spindle-cell/sclerosing rhabdomyosarcomas (SS-RMS) are clinically and genetically heterogeneous. They include three well-defined molecular subtypes, of which those with EWSR1/FUS::TFCP2 rearrangements were described only recently. This study aimed to evaluate five new cases of SS-RMS and to perform a clinicopathological and statistical analysis of all TFCP2-rearranged SS-RMS described in the English literature to more comprehensively characterize this rare tumour type.
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- Chordoma is a rare malignant tumor usually found in young patients, typically affecting the axial skeleton; this report focuses on a case involving a 74-year-old male with a high-grade tumor in the knee.
- Initial biopsies suggested metastatic clear-cell carcinoma, but imaging studies didn’t identify any primary tumors, leading to further investigation.
- Advanced molecular genetic analysis, including methylation profiling, identified the tumor as poorly differentiated chordoma, highlighting the importance of using comprehensive diagnostic tools for rare soft tissue tumors.