Unlabelled: This is the overview of several hospitalized cases of skin tumors this year based on which we analyzed the information in the literature concerning the clinical features, the evolution and therapy of these skin neoplasms. The tumors that develop in the skin fibrous tissue sometimes on a prior lesion need to be analyzed from a multidisciplinary perspective, therefore it is essential for the surgeon, the pathologist and the oncologist to consistently cooperate and to solve all issues related to the evolution of the case, which may be at times less favorable.
Patients And Method: In what follows we will introduce two clinical cases of dermato-fibrosarcoma protuberans (Darier-Ferrand) met in our recent practice this year, accompanied by the data found in the specialized literature concerning the clinical features, evolution and therapy of these quite rare skin lesions.