Ghrelin and Ang 1-7 have cumulative vasodilatory effects on pulmonary vessels.

Unlabelled: Ghrelin is an orexigenic hormone that has been shown to have vasodilator effects. Angiotensin 1-7 (Ang 1-7) is a bioactive component of the renin-angiotensin system and may play an important role in the regulation of cardiovascular homeostasis.

Aim: The aim of this study was to investigate the interaction between ghrelin and a better known vasodilatator, Ang 1-7.

[New insight into nitric oxide involvement in regulation of airways smooth muscle tone].

Unlabelled: All three isoforms of NO synthases (NOS) were localised in the lung and are involved in regulation of airways and pulmonary vessels smooth muscle tone and inflammatory response. The participation of nitric oxide in the regulation of airways smooth muscle has not been understood yet.

Material And Method: We studied age-related variation of NO secretion on three lots of bronchi rats: young (4-6 weeks), adults (2-3 months), old (12-14 months).

Interactions between angiotensin II and phenylephrine on isolated rat renal arteries and veins.

It is know that not only decreased blood flow to the kidney but also obstruction of renal outflow may, in some instances, be a cause of hypertension. In this view were compared angiotensin (Ang) II responses and investigated interactions between Ang II and phenylephrine (Phe) on renal vessels. Studies were performed on renal artery and vein rings without endothelium obtained from young (4 months) and old (12 month of age) male Wistar rats.