Publications by authors named "Mihaela A Ghita"
Real-Time Investigation of Skin Blood Flow Changes Induced by Topical Capsaicin.
Acta Dermatovenerol Croat
October 2017
Capsaicin induces a localized inflammatory process known as neurogenic inflammation upon its topical administration on the skin, due to the release of various neuropeptides from the cutaneous sensory nerve endings. In this study, we investigated real-time skin blood flow changes that occur in neurogenic inflammation induced by topical capsaicin by means of in vivo reflectance confocal microscopy. 27 healthy subjects (15 women and 12 men, mean age ± Standard Deviation: 22.
View Article and Find Full Text PDFBasal cell carcinoma (BCC) is the world's leading skin cancer in terms of frequency at the moment and its incidence continues to rise each year, leading to profound negative psychosocial and economic consequences. UV exposure is the most important environmental factor in the development of BCC in genetically predisposed individuals, this being reflected by the anatomical distribution of lesions mainly on sun-exposed skin areas. Early diagnosis and prompt management are of crucial importance in order to prevent local tissue destruction and subsequent disfigurement.
View Article and Find Full Text PDFArticle Synopsis
- Superficial basal cell carcinoma (sBCC) is a common type of skin cancer that typically appears as red, scaly lesions on the upper body and is usually diagnosed through a skin biopsy.
- Early detection and treatment are essential to prevent further skin damage, even though sBCC grows slowly and rarely spreads.
- The combination of dermoscopy and a new imaging technique called reflectance confocal microscopy (RCM) improves the accuracy of diagnosing sBCC and allows for ongoing monitoring of the condition without invasive procedures.