Investigation of halogenated furanones as inhibitors of quorum sensing-regulated bioluminescence in .

is a Gram-negative marine bacterium that is a model system in the study of quorum sensing (QS). uses multichannel QS, mediated by three signaling molecules. The aim of this study was to synthesize and screen a diverse series of furanones for their potential to inhibit quorum sensing.

Immunomodulation of J774A.1 Murine Macrophages by Strains Isolated From the Human Gastrointestinal Tract and Fermented Foods.

species (recently re-named subsp. ) can be isolated from both either the mammalian gut or specific fermented foods where they may be present at high concentrations. Whilst strains have been proposed as potential probiotic candidates, the ability of resident strains consumed in fermented foods to interact with the host is unclear.

Chitin Attenuates Expression of Virulence Genes .

External signals are crucial for bacteria to sense their immediate environment and fine-tune gene expression accordingly. The foodborne pathogen senses a range of environmental cues in order to activate or deactivate the virulence-inducing transcriptional factor PrfA during transition between infectious and saprophytic lifecycles. Chitin is an abundant biopolymer formed from linked β-(1-4)-N-acetyl-D-glucosamine residues associated with fungi, the exoskeleton of insects and often incorporated into foods as a thickener or stabilizer.