Publications by authors named "Miguel Schon"

Article Synopsis
  • * A case report details a 21-year-old woman with LEMS who initially improved with treatment but developed psychotic symptoms leading to steroid discontinuation and later experienced worsening health, including respiratory distress and difficulties with swallowing.
  • * After undergoing plasmapheresis and starting rituximab, her muscle strength partially improved, but her psychiatric symptoms remained, indicating a potential separate psychiatric issue alongside her neuromuscular condition.
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Article Synopsis
  • The study investigated the risk of acute symptomatic seizures in patients who experience recurrent strokes compared to those having their first stroke, looking at data from stroke patients over a 5-year period.
  • The findings revealed that the risk of seizures was similar for both groups, with 5.1% for recurrent stroke patients and 4.5% for first-time patients, suggesting prior stroke history doesn’t increase seizure risk.
  • Other factors like age, sex, and hemorrhagic changes were linked to seizures only in first-time stroke patients, indicating different risk profiles between the two groups; further research in larger studies is encouraged to validate these results.
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The cerebellar cognitive affective syndrome is a neuropsychiatric syndrome composed of affective (anxiety, depression, euphoria, and emotional lability) and cognitive symptoms (executive, attentional, and visuospatial deficits) that was described in the 1990s. We present the case of a 49-year-old woman with a history of an acute neurological episode at the age of 28, after which she reported a change in personality, brief and alternating periods of depression, hypomania, and mixed episodes, and cognitive impairment that had a major impact on her personal and occupational level of functioning. She was initially diagnosed with bipolar disorder, but a clinical, neuropsychological, and imaging re-evaluation prompted a diagnostic reconsideration in favor of a cerebellar cognitive affective syndrome.

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Purpose: Posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS) are often complicated by vasospasm and ischemia. Monitoring with transcranial color-coded Doppler (TCCD) could be useful, but its role is not established. We studied the incidence of ultrasonographic vasospasm (uVSP) in PRES/RCVS and its relationship with ischemic lesions and clinical outcome.

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Transient global amnesia (TGA) is a neurological syndrome with rather distinctive brain MRI features, namely hyperintense lesion in hippocampus on diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) sequences. Post-traumatic amnesia is another amnestic syndrome which can also show hyperintense lesions in brain MRI due to cytotoxic oedema caused by traumatic brain injury. We present a case of a patient with post-traumatic amnesia with a brain MRI image mimic of TGA.

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