Publications by authors named "Miguel S Serrano"

In a multicenter European retrospective study including 162 patients with COVID-19 occurring in essential thrombocythemia (ET, n = 48), polycythemia vera (PV, n = 42), myelofibrosis (MF, n = 56), and prefibrotic myelofibrosis (pre-PMF, n = 16), 15 major thromboses (3 arterial and 12 venous) were registered in 14 patients, of whom all, but one, were receiving LMW-heparin prophylaxis. After adjustment for the competing risk of death, the cumulative incidence of arterial and venous thromboembolic events (VTE) reached 8.5% after 60 days follow-up.

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Article Synopsis
  • A study of 175 patients with myeloproliferative neoplasms (MPN) during COVID-19 showed a high mortality rate of 48% in those with myelofibrosis (MF), which is significantly higher than the general population.
  • Key factors linked to higher mortality included older age, male gender, lower lymphocyte counts, need for respiratory support, and existing comorbidities, but no significant links were found with essential thrombocythemia or polycythemia vera.
  • While Ruxolitinib treatment was more frequent among those who died, stopping the treatment before COVID-19 was associated with increased mortality, indicating the need for further research on how treatment interruptions affect survival in M
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Hopperburn is a non-contagious disease of plants caused by the direct feeding damage of certain leafhoppers and planthoppers. Although long studied, especially with Empoasca spp. leafhoppers (Cicadellidae: Typhlocybinae), the mechanisms underlying hopperburn have only recently been elucidated.

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Two compounds that together constitute the female sex pheromone of the pink hibiscus mealybug (PHM), Maconellicoccus hirsutus, were isolated, identified, and synthesized. They are (R)-2-isopropenyl-5-methyl-4-hexenyl (S)-2-methylbutanoate [common name is (R)-lavandulyl (S)-2-methylbutanoate] and [(R)-2,2-dimethyl-3-(1-methylethylidene)cyclobutyl]methyl (S)-2-methylbutanoate [which we refer to as (R)-maconelliyl (S)-2-methylbutanoate]. Maconelliol is an unusual cyclobutanoid monoterpene, and its structure has been established by enantioselective synthesis from precursors of known structure and configuration.

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