Publications by authors named "Miguel Pinto-Gouveia"

The Gorlin-Goltz syndrome is a rare autosomal dominant hereditary condition, with complete penetrance and variable expressivity. Characterized by the appearance of multiple basaliomas, and often the development of keratocyst, it can also express itself by the presence of palmar/plantar depressions, calcification of brain sickle, and skeletal birth defects, although less frequently. This article presents two cases involving direct relatives, referred after the identification of several basaliomas and jaw cysts.

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Non-steroidal, anti-inflammatory drugs, followed by antibiotics, are the main causes of fixed drug eruption. They provoke one or several round erythematous or bullous lesions that recur in the same place after taking the causative medication. A positive patch test on residual, lesional skin can replace satisfactorily oral reintroduction.

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A 45-year-old man presented with follicular exanthema in his lower limbs, alternating bowel habits and significant weight loss. His medical history included seronegative arthritis, bipolar disease and an inconclusive diagnostic laparoscopy. Diagnostic work up revealed microcytic anaemia and multivitamin deficiency.

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The type of cutaneous infection varies mainly according to the patient's immune status, and the disseminated form is mostly found in the context of immunosuppression. We report the case of a 62-year-old male who was under long-term systemic corticosteroid therapy and presented with a 7-month history of multiple painless cutaneous lesions at various stages of development: papules, nodules, pustules and hemorrhagic crusts, as well as small erosions and ulcers distributed over the limbs and scalp. Cutaneous biopsy showed a suppurative granulomatous infiltrate with abscess formation.

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Multiple minute digitate hyperkeratosis is a rare, non-follicular dermatosis, with fewer than 30 cases described worldwide. It can be either acquired or inherited in an autosomal dominant pattern. We describe the case of an 83-year old patient with life-long, multiple, digitate, milimetric lesions, and a positive family history for the same dermatosis.

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Synopsis of recent research by authors named "Miguel Pinto-Gouveia"

  • - Miguel Pinto-Gouveia's research primarily focuses on rare dermatological conditions, exploring their diagnosis and treatment options, as evidenced by his work on Gorlin-Goltz syndrome and multiple minute digitate hyperkeratosis.
  • - His studies highlight the complex presentations and variable expressivity of hereditary conditions, as well as the necessity for accurate diagnosis in cases where similar symptoms may indicate different underlying diseases, such as the misidentification of condylomata lata as Buschke-Löwenstein tumor.
  • - Pinto-Gouveia's findings suggest the importance of considering broader medical histories and potential environmental factors, as seen in his case reports that link dermatological manifestations with gastrointestinal diseases and immunosuppression, indicating a need for comprehensive patient evaluation.