Effects of Coffee on Sirtuin-1, Homocysteine, and Cholesterol of Healthy Adults: Does the Coffee Powder Matter?

Background: Coffee is one of the most popular beverages globally and contains several bioactive compounds that are relevant to human health. Many nutritional strategies modulate sirtuin-1, thereby impacting aging and cardiometabolic health. This study investigated the influence of different blended coffees on serum sirtuin-1, blood lipids, and plasma homocysteine.

Nursing training and retraining on cardiopulmonary resuscitation: a theoretical-practical intervention.

Objective: To analyze the retention of knowledge and skills of nursing professionals following training and retraining on cardiopulmonary resuscitation.

Method: This is an intervention, prospective, and analytical study in which 56 nursing professionals received theoretical and practical training in in-service cardiopulmonary resuscitation. Nine months after the first training (T1), these professionals participated in a retraining (T2).

Multivessel Woven Coronary Artery Disease.

Woven coronary disease is a rare pathology with unknown etiology. Although initially considered benign, recent publications report myocardial ischemia caused by the affected vessel. Since most patients are asymptomatic, long-term follow-up to understand its behavior is mandatory.

Retention of Cardiopulmonary Resuscitation Skills in Medical Students.

Background: Reduction of mortality and sequelae of cardiac arrest depends on an effective and fast intervention, started as soon as possible. Basic life support involves a series of steps that may be initiated out of the hospital setting and taught to any person in specific courses. However, it is important that the rescuers retain the knowledge and skills to perform cardiopulmonary resuscitation (CPR), as one never knows when they will be required.

Combination of amlodipine and enalapril in hypertensive patients with coronary disease.

Background: Patients (pts) with stable coronary artery disease (CAD) can benefit from a decrease in the blood pressure (BP), according to recent studies.

Objective: To evaluate the efficacy and tolerability of the fixed combination: amlodipine + enalapril, when compared to amlodipine in the normalization of the diastolic arterial pressure (DAP) (<85 mmHg), in pts with CAD and systemic arterial hypertension (SAH).

Methods: Double-blind and randomized study, with two groups of pts with DAP > or =90 and <110 mmHg and CAD.

Advanced cardiac life support training improves long-term survival from in-hospital cardiac arrest.

Context: Advanced cardiac life support (ACLS) training was introduced to bring order and a systematic approach to the treatment of cardiac arrest by professional responders. In spite of the wide dissemination of ACLS training, it has been difficult to demonstrate improved outcome following such training.

Objective: To determine the value of formal ACLS training in improving survival from in-hospital cardiac arrest.

Monophasic versus biphasic waveform shocks for atrial fibrillation cardioversion in patients with concomitant amiodarone therapy.

Aims: With transthoracic cardioversion of atrial fibrillation (AF), biphasic are more effective than monophasic waveforms. We sought to determine the ideal energy levels for biphasic waveforms. Methods We compared biphasic truncated exponential waveforms with monophasic damped sine waveform defibrillators, in a prospective, single-centre, randomized (1:1 ratio) study.

Stratifying the risk in unstable angina with dobutamine stress echocardiography.

Objective: To evaluate the role of dobutamine stress echocardiography (DSE) in the risk stratification of low to moderate risk unstable angina (UA) patients, to predict the combined clinical outcome of cardiovascular death, myocardial infarction (MI), recurrent UA and the need of revascularization procedures in a 6 month period.

Methods: Multicenter prospective study. Patients should be admitted to the hospital and asymptomatic in the last 24 hours.

[Analysis of the intra-hospital attending of ventricular fibrilation/ventricular taquicardia simulated events].

Objective: To analyze the time intervals between the beginning of the Ventricular Fibrilation/Ventricular Taquicardia (VF/VT) and the main procedures made.

Methods: Twenty VF/VT simulations were performed and filmed in a hospital environment, using a static mannequin, on random days at random times. All teams had the same level of skills.

Preliminary in-hospital experience with a fully automatic external cardioverter-defibrillator.

Background: Ventricular fibrillation (VF) and ventricular tachycardia (VT) are frequently present as initial rhythms during in-hospital cardiac arrest. Although ample evidence exists to support the need for rapid defibrillation, the response to in-hospital cardiac arrest remains without major advances in recent years. The delay between the arrhythmic event and intervention is still a challenge for clinical practice.