Publications by authors named "Miguel Medina Gomez"
Article Synopsis
- Influenza A virus (IAV) pandemics, such as the one in Mexico in 2009, pose a significant health risk with millions of deaths and no effective vaccine available due to gene mutations and genome segment variability.
- Researchers utilized bioinformatics to design immunogenic peptides based on the IAV proteins neuraminidase (NA) and hemagglutinin (HA), focusing on properties like promiscuity and conservation across strains.
- Experimental results showed that peptides P11 and P14 successfully prompted antibody production in immunized rabbits and mice, with capabilities to recognize IAV strains and neutralize viral particles, confirming the efficacy of the designed peptides.
