Publications by authors named "Miguel J S Bortolini"

The emergence of COVID-19 caused by SARS-CoV-2 prompted an unprecedented global response to develop vaccines at an accelerated pace. Messenger RNA (mRNA) and adenovirus vector vaccines emerged as the frontrunners in global immunization efforts, significantly reducing hospitalization, severity, and mortality, supplemented by inactivated virus-based vaccines in developing countries. However, concerns regarding adverse effects, including allergic reactions, have been raised.

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Since the World Health Organization declared the global COVID-19 state of emergency in early 2020, several vaccine candidates have emerged to control SARS-CoV-2, and some of them have been approved and implemented in vaccination campaigns worldwide. Although clinical trials for these vaccines have been carried out using highly controlled methods with accurate immunological tests, clinical questionnaires did not include questions concerning the physical activity profile among volunteers. It has been well established that physical activity plays a pivotal role in the immune response after vaccination, led by the activation of cytokines, antibodies, and cells.

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Objective: To analyze the association between anthropometric variables and cardiovascular risk factors in adults and older adults of Rio Branco, Acre.

Methods: A population-based cross-sectional study with 641 adults and 957 older adults was conducted. The statistical analyses consisted of the distribution of anthropometric variables according to the cardiovascular risk factors by frequency and dispersion measures.

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Objective: The objective of this study was to evaluate and correlate hematologic indices, vitamin B levels, and depression in patients with suspected reflux (LPR) treated with proton pump inhibitor (PPI).

Methods: This was a prospective study with a population (n = 23) consisted of patients with suspected LPR and treated with 2 daily doses of Omeprazole 40 mg (80 mg or full dose). The study volunteers performed a complete blood count and vitamin B dosage before and after 3 and 6 months of treatment, as well as depression screening using the Center of Epidemiologic Studies-Depression (CES-D) questionnaire before and after 6 months of treatment.

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Unlabelled: This study aimed to verify whether salivary total protein (STP) would reflect anaerobic threshold in elderly athletes subjected to an incremental exercise test.

Methods: Seven elderly elite athletes (EEA) and six physically active elderly men (PAE) completed a treadmill protocol in which blood and saliva samples were collected.

Results: Blood lactate (BL) and STP increased significantly in EEA during the test (0.

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Objective: The present systematic review aimed to verify the effect of resistance and combined training on the inflammatory profile of breast cancer survivors.

Design: The searches were made on the platforms PsycINFO, PubMed, Cochrane, Science Direct and Scopus, from 1996 to 2017, using the keywords: cancer survivors, cancer treatment, cancer patients, breast cancer, inflammation, inflammatory profile, immune function, resistance training, strength training, weight training, physical activity, concurrent training and combined training. References of selected articles were also considered.

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Physical exercise has been implicated in several immunophysiological improvements, particularly during the aging process, when an immunocompromised status could be established. is a protozoan parasite that causes a widespread opportunistic infection, which may present severe consequences, mainly to the fetus and immunocompromised patients. It is estimated that one-third of the human population worldwide has been infected by this parasite, being the reactivation during immunesenescence an unexplored public health issue.

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Saliva provides a convenient and noninvasive matrix for assessing specific physiological parameters, including some biomarkers of exercise. We investigated whether the total protein concentration of whole saliva (TPWS) would reflect the anaerobic threshold during an incremental exercise test. After a warm-up period, 13 nonsmoking men performed a maximum incremental exercise on a cycle ergometer.

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