Publications by authors named "Miguel Espirito-Santo"

Introduction And Objectives: Concerns regarding the consequences of ionizing radiation (IR) have been increasing in the field of interventional cardiology (IC). There is little information on reported national and local radiation diagnostic reference levels (DRLs) in catheterization laboratories in Portugal. This study was designed to assess the IR dose exposure during complex percutaneous coronary intervention (PCI), and to set the respective DRLs and future achievable doses (ADs).

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Introduction And Objectives: Coronary chronic total occlusions (CTOs) of the right coronary artery (RCA) are a relatively common finding in the context of coronary angiography. However, the benefit of revascularization remains controversial.

Methods: A single-center retrospective cohort analysis prospectively collected outcomes of CTO patients undergoing percutaneous coronary intervention (PCI) in 2019 and 2020.

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Introduction And Objectives: Coronary chronic total occlusions (CTOs) are relatively common findings in patients with type 2 diabetes mellitus (T2DM). However, the indication for percutaneous coronary intervention (PCI) and its clinical benefit in these patients remain controversial.

Methods: A single-center retrospective cohort study with prospectively collected outcomes was carried out with CTO patients undergoing PCI in 2019 and 2020.

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Background: Pretreatment antithrombotic strategies in non-ST elevation acute coronary syndromes (NSTE-ACS) during hospitalization is still a matter of contention within the cardiology community. Our aim was to analyze in-hospital and one-year follow-up outcomes of patients with NSTE-ACS pretreated with dual antiplatelet therapy (DAPT) versus single antiplatelet therapy (SAPT).

Methods: A retrospective study was carried out with NSTE-ACS patients who planned to undergo an invasive strategy and were included in the Portuguese Registry of ACS between 2018 and 2021.

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Fabry disease is a rare lysosomal storage disorder caused by mutations in the gene, resulting in reduced or absent α-Gal A activity. Migalastat is an oral chaperone therapy for Fabry patients with amenable variants. We previously reported a case of a 60-year-old male patient with a classic phenotype of Fabry disease, presenting with two variants: p.

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For humans as social beings, other people's hands are highly visually conspicuous. Exceptionally striking are hands in other than natural configuration which have been found to elicit distinct brain activation. Here we studied response strength and lateralization of this activation using event-related potentials (ERPs), in particular, occipito-temporal N1 responses as correlates of activation in extrastriate body area.

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Hands, much like faces, convey social information, instructions and intentions to an observer. While the neural processes of face perception have been widely studied, it was only recently that fMRI identified occipito-temporal areas sensitive to static images of hands as body parts. To complement these studies with fine-grained timing information, we measured event-related EEG potentials (ERPs) from 33 subjects who were presented with static images of hands versus faces, whole bodies, and inanimate objects as controls.

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