Publications by authors named "Miguel Delgado-Rodriguez"

Article Synopsis
  • Periodontal disease (PD) can worsen insulin resistance during pregnancy, increasing the risk of gestational diabetes mellitus (GDM).
  • A systematic review and meta-analysis of 176 studies identified 11 valid studies involving 2032 pregnant women, with 572 developing GDM.
  • Results indicated that PD is a significant risk factor for GDM (OR=1.83), suggesting the need for oral health programs for women planning to conceive to better control metabolic health and reduce complications.
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Aims: This study aims to identify a posteriori dietary patterns with a sex approach and to evaluate their association with metabolic syndrome criteria.

Methods: Cross-sectional study conducted in 6821 men and women between 55 and 75 years of age. Forty-two food groups were analyzed from dietary information collected with food frequency questionnaires, using principal component analysis and cluster analysis and then information from both statistical methods was compared.

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The aim of our cross-sectional and longitudinal study is to assess the relationship between daytime and night-time sleep duration and health-related quality of life (HRQoL) in adults with metabolic syndrome after a 1-year healthy lifestyle intervention. Analysis of the data from 2119 Spanish adults aged 55-75 years from the PREDIMED-Plus study was performed. Sleep duration was assessed using a wrist-worn accelerometer.

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Cognitive decline has been reported as a short-term sequela in patients hospitalized for coronavirus disease-19 (COVID-19). Whether COVID-19 is associated with late cognitive impairment in older free-living individuals with high cardiovascular risk, a group at greater risk of cognitive decline, is unknown. We determined this association of COVID-19 through a longitudinal evaluation of post-COVID-19 cognitive performance and impairment as post hoc analysis in 5,179 older adults (48% female) with mean (SD) age 68.

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Background: The COVID-19 lockdown represented an immense impact on human health, which was characterized by lifestyle and dietary changes, social distancing and isolation at home. Some evidence suggests that these consequences mainly affected women and altered relevant ongoing clinical trials. The aim of this study was to evaluate the status and changes in diet, physical activity (PA), sleep and self-reported health status (SRH) as perceived by older adult men and women with metabolic syndrome during the COVID-19 lockdown.

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The aim of this study was to evaluate the possible impact of the COVID-19 pandemic on prevalence rates and self-reported changes in patterns of alcohol use among first-year university students in Spain, considering the risk of problematic alcohol use. A serial cross-sectional study based on the uniHcos project was carried out. Data from 10 518 first-year university students (73.

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Objective: To estimate the environmental impact of a dietary intervention based on an energy-reduced Mediterranean diet (MedDiet) after one year of follow-up.

Methods: Baseline and 1-year follow-up data were used for 5800 participants aged 55-75 years with metabolic syndrome in the PREDIMED-Plus study. Food intake was estimated through a validated semiquantitative food consumption frequency questionnaire, and adherence to the MedDiet was estimated through the Diet Score.

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Scope: Diets rich in polyphenols has been associated with better cognitive performance. The aim of this study is to assess the relationship between microbial phenolic metabolites (MPM) in urine and cognition in the context of an older population at high cardiovascular risk.

Methods And Results: A cross-sectional analysis is conducted in 400 individuals of the PREDIMED-Plus study.

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Background: Cross-sectionally, older age and obesity are associated with increased coronavirus disease-2019 (COVID-19) risk. We assessed the longitudinal associations of baseline and changes in adiposity parameters with COVID-19 incidence in older adults at high cardiovascular risk.

Methods: This analysis included 6874 men and women (aged 55-75 years) with overweight/obesity and metabolic syndrome in the PREDIMED-Plus lifestyle intervention trial for cardiovascular risk reduction.

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Objective: To determine the association between different pelvic floor disorders and the presence of sexual dysfunction in women.

Method: An observational study of non-pregnant women was carried out in Spain in 2021 and 2022. To assess the presence of pelvic floor problems, the Pelvic Floor Distress Inventory (PFDI-20) was used, consisting of the subscales Pelvic Organ Prolapse Distress Inventory-6 (POPDI-6; prolapse symptoms), Colorectal-Anal Distress Inventory (CRADI-8; colorectal symptoms), and Urinary Distress Inventory-6 (UDI-6; urinary symptoms).

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Background: The coronavirus disease 2019 (COVID-19) has serious physiological and psychological consequences. The long-term (>12 weeks post-infection) impact of COVID-19 on mental health, specifically in older adults, is unclear. We longitudinally assessed the association of COVID-19 with depression symptomatology in community-dwelling older adults with metabolic syndrome within the framework of the PREDIMED-Plus cohort.

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Background: It has been proposed that physical activity (PA) could prevent cognitive decline.

Objective: To evaluate the association between changes in PA and changes in cognitive function in a cohort of adults with metabolic syndrome.

Methods: Longitudinal observational study including 5,500 adults (mean age 65 years, SD = 5; women = 49.

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Article Synopsis
  • The World Health Organization estimates that 20% of university students have faced major depressive disorder, and factors like low omega-3 fatty acids and vitamin D, found in fish, may play a role in depression.
  • A study surveyed 11,485 Spanish university students to assess the prevalence of depression and fish consumption habits, finding a 10.5% depression rate, particularly among women, older students, and those living away from home.
  • The research indicated that 67% of students met fish intake recommendations, with 44.2% consuming fish 1-2 times per week; low fish consumption was linked to an increased risk of depression, but individual circumstances were the most significant factors influencing disorder development.
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Background And Aims: The association between changes in ultra-processed food (UPF) consumption and cardiometabolic risk (CMR) factors remains understudied. We evaluated the association between changes in UPF consumption over 12 months of follow-up and changes in CMR factors in adults diagnosed with metabolic syndrome.

Methods: We analysed data from 5373 adults (aged 55-75 years) participating in the PREDIMED-Plus trial.

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Background: Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function.

Objective: To prospectively evaluate the association between nut consumption and 2-y changes in cognitive performance in older adults at cognitive decline risk.

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Background: Dietary patterns can produce an environmental impact. Changes in people's diet, such as the increased consumption of ultra-processed food (UPF) can not only influence human health but also environment sustainability.

Objectives: Assessment of the impact of 2-year changes in UPF consumption on greenhouse gas emissions and water, energy and land use.

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Aims: To assess the comparative effects of glucagon-like peptide-1 receptor agonists (GLP-1RA), 4-dipeptidyl peptidase inhibitors (DPP-4I), and metformin treatment during one year on metabolic syndrome (MetS) components and severity in MetS patients.

Methods: Prospective study (n = 6165 adults) within the frame of PREDIMED-Plus trial. The major end-point was changes on MetS components and severity after one- year treatment of GLP-1RA, DPP-4I, and metformin.

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Article Synopsis
  • The article with DOI: 10.3389/fendo.2022.868795 has been revised or corrected.
  • The corrections may address errors, updates, or clarifications needed for the original content.
  • Readers should refer to the correction to ensure they are accessing the most accurate information.
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Article Synopsis
  • The Mediterranean diet (MedDiet) has been linked to a reduced risk of cardiovascular disease (CVD) through randomized trials, but its causal effects in nonrandomized studies are often questioned.
  • The SUN project, which analyzed data from 18,419 participants over 20 years, aimed to demonstrate that the observed benefits of the MedDiet on CVD risk were indeed causal rather than coincidental.
  • Findings revealed that increasing adherence to the MedDiet correlated with a 29% reduction in CVD risk and could delay the onset of the disease by nearly 8 years, supporting the diet's preventive role through various analytical strategies.
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Carotenoid intake has been reported to be associated with improved cardiovascular health, but there is little information on actual plasma concentrations of these compounds as biomarkers of cardiometabolic risk. The objective was to investigate the association between circulating plasma carotenoids and different cardiometabolic risk factors and the plasma fatty acid profile. This is a cross-sectional evaluation of baseline data conducted in a subcohort (106 women and 124 men) of an ongoing multi-factorial lifestyle trial for primary cardiovascular prevention.

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Background Dietary polyphenol intake has been associated with a decreased risk of hyperuricemia, but most of this knowledge comes from preclinical studies. The aim of the present study was to assess the association of the intake of different classes of polyphenols with serum uric acid and hyperuricemia. Methods and Results This cross-sectional analysis involved baseline data of 6332 participants.

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Article Synopsis
  • Metabolic syndrome (MetS) is a major global health issue, and identifying individual patient characteristics can help improve management strategies.
  • The study used common health check-up data to categorize MetS patients based on factors like body measurements, clinical history, and lab results.
  • Four distinct patient clusters were found, highlighting specific issues like glucose disorders, mild MetS, high liver enzyme levels, and cholesterol problems, suggesting that liver health is crucial for tailored MetS treatment.
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Among university students there has been evidence that the COVID-19 pandemic increased their psychological distress, exacerbated by social restrictions. The main objective of this study was to explore the impact of the COVID-19 pandemic on the prevalence and patterns of cannabis use among university students, in contrast to previous trends since 2012. Data from 10,522 first-year university students (73.

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