Publications by authors named "Miguel Cepeda"
J Mol Model
November 2013
Article Synopsis
- The study investigated how L-aminoglucosidic stereoisomers, specifically rhodostreptomycins A (Rho A) and B (Rho B), interact with cations like Mg(2+), Ca(2+), and H(+), using quantum mechanical methods and docking studies.
- Both stereoisomers exhibit similar properties against the bacterium Helicobacter pylori, but Rho B has a stronger affinity for Mg(2+) ions, resulting in its hydration.
- The results indicate that Rho B forms a more stable complex with hydrated Mg(2+) compared to Rho A, and docking suggests that both molecules bind to these cations through hydrogen bonding.
