Impact of the MIC of piperacillin-tazobactam on the outcome of patients with bacteremia due to extended-spectrum-β-lactamase-producing Escherichia coli.

We investigated the impact of the piperacillin-tazobactam MIC in the outcome of 39 bloodstream infections due to extended-spectrum-β-lactamase-producing Escherichia coli. All 11 patients with urinary tract infections survived, irrespective of the MIC. For other sources, 30-day mortality was lower for isolates with a MIC of ≤ 2 mg/liter than for isolates with a higher MIC (0% versus 41.

Long-term outcome of patients after a single interruption of antiretroviral therapy: a cohort study.

Background: To describe the long term outcome of patients who interrupted highly active antiretroviral therapy (HAART) once, identify the variables associated with earlier need to re-start HAART, and the response when therapy was resumed. A retrospective observational cohort of 66 adult patients with HIV-1 infection who interrupted HAART with a CD4+cell count ≥ 350 cells/μL and undetectable viral load (VL) was performed. The pre-established CD4+ cell count for restarting therapy was 300cells/μL.

[Arthroplasty-related infection: incidence, risk factors, clinical features, and outcome].

Introduction: There is little information about the overall incidence, risk factors, and clinical management of arthroplasty-related infection in Spain.

Methods: The incidence of surgical site infection (SSI) in hip and knee arthroplasty from 2001 to 2005 was determined. Risk factors for SSI were investigated in 435 patients using multivariate logistic regression analysis.

[Epidemiology, clinical features and prognosis of infections due to Stenotrophomonas maltophilia].

Introduction: Stenotrophomonas maltophilia is a multiresistant pathogen that is being isolated with increasing frequency from patients with predisposing factors. Few studies have assessed the epidemiology and clinical relevance of this pathogen in various types of patients from general hospitals.

Methods: This is a prospective study performed in the cohort of patients with infection due to S.

[Acinetobacter baumannii bacteremia: clinical and prognostic features].

Objective: The incidence, clinical features, and prognosis of bacteremia due to Acinetobacter baumannii were investigated.

Methods: Prospective study of all episodes of A. baumanii bacteremia detected during the period of January 1995 to December 1998.