The Feasibility, Acceptability, and Utility of Mantente REAL: the Culturally Adapted Version of keepin' it REAL for Mexico.

A binational team of investigators culturally adapted, implemented, and tested the efficacy in Mexico of keepin' it REAL, a US-designed prevention intervention for youth. This article reports on the social validity of the adapted intervention by assessing its feasibility, acceptability, and utility, as perceived by participating middle school students, teachers/implementers, and school administrators. Middle schools (N = 36) were randomly assigned to (1) the culturally adapted version for Mexico (Mantente REAL), (2) the original intervention from the USA (keepin' it REAL) translated into Spanish, or (3) a control condition (treatment as usual).

Binational Cultural Adaptation of the keepin' it REAL Substance Use Prevention Program for Adolescents in Mexico.

Sharp increases in substance use rates among youth and the lack of evidence-based prevention interventions in Mexico are a major concern. A team of investigators from Mexico and the USA are actively addressing this gap by culturally adapting keepin' it REAL (kiR)-a former US SAMHSA model program-for Mexico. This paper reports on the processes and outcomes of the cultural adaptation of kiR for adolescents in Mexico.

Revisiting a physiologically based pharmacokinetic model for cocaine with a forensic scope.

A whole-body permeability-rate-limited physiologically based pharmacokinetic (PBPK) model for cocaine was developed and adjusted with the pharmacokinetic data from studies with animals and reparametrized scaling to humans with the aim to predict the concentration-time profiles of the drug in blood and different tissues in humans. Estimated time course concentrations could be used as an interpretation tool by forensic toxicologists. The model estimations were compared successfully with pharmacokinetic parameters and time to peak for some effects reported in the literature.

History of child sexual abuse among women consuming illicit substances in Mexico City.

Introduction: Child sexual abuse (CSA) is a pervasive problem that has been linked to numerous developmental, social, health, and substance use consequences. Nevertheless, the relationship between CSA and the consumption of psychoactive substances has not been adequately studied in Mexico. The present study aims to examine this association between history of CSA and illicit substance use and associated risk behaviors in a sample of young adult women in Mexico City.

Years of life lost (Yll) attributable to alcohol consumption in Mexico City.

The aim of this study was to estimate the YLL attributable to alcohol consumption in Mexico City from 2006 - 2012. Vital statistics on mortality attributable to alcohol consumption from the INEGI (Instituto Nacional de Estadística y Geografía) were used to determine YLL as well as the average age of death in relation to different age ranges by sex. A total estimate of 168,607 YLL was obtained, with an average loss of 18.