Publications by authors named "Miguel Angel Martinez Alvarez"
A randomized, double-blind study on the efficacy of oral domperidone versus placebo for reducing SARS-CoV-2 viral load in mild-to-moderate COVID-19 patients in primary health care.
Alejandro Rabanal Basalo Mercedes Navarro Pablos Nuria Viejo Pinero María Luz Vila Méndez Verónica Molina Barcena
Ann Med
October 2023
Introduction: The clinical effect of domperidone against COVID-19 has been investigated in a double-blind phase III clinical trial (EudraCT number 2021-001228-17). Domperidone has shown in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potential immudolatory properties through the stimulation of prolactin secretion.
Patients And Methods: The efficacy of oral domperidone plus standard of care (SOC; = 87) versus placebo plus SOC ( = 86) was evaluated in a 28-day randomized double-blind multicentre study in primary health care centres.
Article Synopsis
- A study on chronic heart failure (CHF) is being conducted to identify factors that predict disability and hospitalisation in patients over a year.
- * The research involves a cohort of 557 patients in Madrid with specific CHF criteria, using the WHO Disability Assessment to measure outcomes.
- * The study has ethical approval and aims to disseminate findings through peer-reviewed journals and medical conferences.