Publications by authors named "Miguel Angel Escrig"
Pharmacol Biochem Behav
January 2014
Article Synopsis
- Hydrogen peroxide (H2O2) plays a key role in the brain's conversion of ethanol (EtOH) to acetaldehyde, influenced by the enzyme catalase and affected by H2O2 levels.
- The research investigates the impact of the MAO-A inhibitor clorgyline on locomotion and voluntary EtOH intake in mice, revealing that it reduces both behaviors selectively.
- Findings suggest that H2O2 generated from biogenic amines via MAO-A activity is crucial for producing brain acetaldehyde, which might influence neurobehavioral effects of ethanol.
