Can ICD Electrograms Help Ventricular Tachycardia Ablation?: Results From the Multicenter Randomized AIDEG-VTA Trial.

Background: The results of ablation of sustained monomorphic ventricular tachycardia (SMVT) are suboptimal. For many patients with implantable cardioverter-defibrillators (ICDs), ICD electrograms (ICD-EGs) provide the only available information on SMVT. ICD-EGs have the ability to distinguish morphologically distinct SMVT and can be used for pace mapping.

Electrophysiological Phenotype-Genotype Study of Sustained Monomorphic Ventricular Tachycardia in Inherited, High Arrhythmic Risk, Left Ventricular Cardiomyopathy.

Background: Among inherited cardiomyopathies involving the left ventricle, whether dilated or not, certain genotypes carry a well-established arrhythmic risk, notably manifested as sustained monomorphic ventricular tachycardia (SMVT). Nonetheless, the precise localization and electrophysiological profile of this substrate remain undisclosed across different genotypes.

Methods: Patients diagnosed with cardiomyopathy and left ventricle involvement due to high-risk genetic variants and SMVT treated by electrophysiological study were recruited from 18 European/US centers.

Spanish catheter ablation registry. 23rd official report of the Heart Rhythm Association of the Spanish Society of Cardiology (2023).

Introduction And Objectives: We report the results of the 2023 Spanish catheter ablation registry.

Methods: Procedural data were collected and incorporated into the REDCap platform by all participating centers through a specific form.

Results: There were 104 participating centers in 2023 compared with 103 in 2022.

Prevalence of bleeding secondary to anticoagulation and mortality in patients with atrial fibrillation admitted with SARS-CoV-2 infection.

Introduction And Purpose: Atrial fibrillation (AF) is common in patients admitted with severe COVID-19. However, there is limited data about the management of chronic anticoagulation therapy in these patients. We assessed the anticoagulation and incidence of major cardiovascular events in hospitalized patients with AF and COVID-19.

Absence of relevant QT interval prolongation in not critically ill COVID-19 patients.

SARS-CoV-2 is a rapidly evolving pandemic causing great morbimortality. Medical therapy with hydroxicloroquine, azitromycin and protease inhibitors is being empirically used, with reported data of QTc interval prolongation. Our aim is to assess QT interval behaviour in a not critically ill and not monitored cohort of patients.

Utility and feasibility of the CartoUnivu™ system for atrial flutter ablation in patients with mechanical prosthetic valves.

Ablation of macroreentrant atrial tachycardia in patients with mechanical prosthetic valves represents a challenge for electrophysiologists, because of the complexity of the procedure and the potential complications. Moreover, the need for fluoroscopy in this type of procedure is greater, due to the risk of interference between the prosthetic valve and the ablation or mapping catheter. We present two cases of patients with mechanical prosthetic valves and atrial flutter who underwent successful ablation with no complications using the CartoUnivu™ tool, which integrates the electroanatomical map and the fluoroscopy image.

Prognostic impact of misdiagnosis of cardiac channelopathies as epilepsy.

Introduction: Cardiac channelopathies are a frequent cause of sudden cardiac death (SCD) and often manifest with convulsive syncope, leading to a misdiagnosis of epilepsy. We aim to evaluate the clinical impact of epilepsy misdiagnosis in a cohort of patients with cardiac channelopathies.

Methods: Fifty probands/families with a cardiac channelopathy were included.

Effect of pulmonary vein catheter ablation on kidney function in patients with atrial fibrillation. A prospective cohort study.

Introduction And Objectives: Several studies have linked the presence of atrial fibrillation (AF) with reduced estimated glomerular filtration rate (eGFR). Our objective was to compare changes in eGFR in patients with AF after pulmonary vein (PV) ablation depending on the success of the technique, as well as to examine the relationship between eGFR and several biomarkers.

Methods: Prospective cohort of patients with AF referred to our center for PV ablation with a 1-year follow-up.

Functional characterization of a novel frameshift mutation in the C-terminus of the Nav1.5 channel underlying a Brugada syndrome with variable expression in a Spanish family.

Introduction: We functionally analyzed a frameshift mutation in the SCN5A gene encoding cardiac Na(+) channels (Nav1.5) found in a proband with repeated episodes of ventricular fibrillation who presented bradycardia and paroxysmal atrial fibrillation. Seven relatives also carry the mutation and showed a Brugada syndrome with an incomplete and variable expression.

Genetic testing of patients with long QT syndrome.

Congenital long QT syndrome is mainly caused by mutations in the KCNQ1, KCNH2 and SCN5A genes. The aim of this study was to investigate the prevalence of mutations in these three genes in patients with long QT syndrome or idiopathic ventricular fibrillation seen at our center. The study included nine patients with long QT syndrome and four with idiopathic ventricular fibrillation.

[Spanish Catheter Ablation Registry. Fifth official report of the Spanish Society of Cardiology Working Group on Electrophysiology and Arrhythmias (2005)].

Introduction And Objectives: The findings (i.e., success and complication rates) of the 2005 Spanish Catheter Ablation Registry, as prepared by the Spanish Society of Cardiology Working Group on Electrophysiology and Arrhythmias, are presented.

[Spanish catheter ablation registry. Fourth official report of the spanish society of cardiology working group on electrophysiology and arrhythmias (2004)].

Introduction: This article details the findings (i.e., success and complication rates) of the 2004 Spanish Catheter Ablation Registry, which was established by the Spanish Society of Cardiology Working Group on Electrophysiology and Arrhythmias.

[Spanish Registry of Catheter Ablation. Third Official Report of the Working Group on Electrophysiology and Arrhythmias of the Spanish Society of Cardiology (2003)].

Introduction: The results of the Third Spanish Catheter Ablation Registry, developed by the Working Group on Electrophysiology and Arrhythmias, are presented for the third consecutive year (2003).

Material And Method: In contrast to previous years, data were collected in two different ways at the discretion of the participating center. Retrospective were obtained with a standard questionnaire, as in previous years.

[Spanish Registry on Catheter Ablation. Second official report of the Working Group on Electrophysiology and Arrhythmias of the Spanish Society of Cardiology (2002)].

Introduction And Objectives: We present the results (success rates and complication rates) for the second consecutive year of the 2002-Spanish Catheter Ablation Registry, developed by the Spanish Society of Cardiology.

Material And Method: Data were collected retrospectively by questionnaires sent to all interventional cardiology laboratories in Spain. The outcomes and complications of ablation procedures performed during 2002 were classified according to the substrate or mechanism of arrhythmia treated.