[Differential diagnosis and management of intramuscular myxomas: A review of our experience].

Background: Intramuscular myxoma is a rare benign soft tissue tumour of mesenchymal origin, which appears as a painless mass of slow growth. Early diagnosis is important in order to differentiate it from other entities, especially soft tissue sarcoma.

Clinical Cases: Two cases, both women with a mean age of 52.

Breast cancer screening: have there been any changes during the last decade? A study in a Spanish unit.

Background: Breast screening programs in Spain cover almost 100% of population. The objective of the present study was to analyze if there have been any changes during the last decade in our breast screening unit (Unidad de Prevención del Cáncer de Mama de Castellón) that can also be extrapolated to other breast screening units.

Methods: We conducted a retrospective and descriptive analysis reviewing patients seen in our breast screening unit between January 1, 2000 and December 31, 2009.

Debating the mathematical model to validate the sentinel lymph biopsy techniques in breast cancer patients. The danger of bias and its practical implications.

Background: Sentinel node biopsy (SNB) is an effective alternative to axillary lymph node dissection (ALD) for axillary staging. SNB (test) needs a validation period in which ALD (the gold standard) is always performed. Sensitivity, specificity and predictive values (PV) are used to define the accuracy of the procedure.

Disease-free survival and prognostic significance of metastatic lymph node ratio in T1-T2 N positive breast cancer patients. A population registry-based study in a European country.

Background: The ratio of positive lymph nodes between the total number of harvested lymph nodes (metastatic lymph node ratio, MLNR) has been proposed as an alternative to the total number of lymph nodes alone in predicting outcomes for patients with breast cancer. Because there can be differences between European and non-European populations, the authors present the first study analyzing MLNR influence over disease-free survival (DFS) by using a population-based cancer registry in a European country.

Methods: Data from 441 patients with T1-2 N1-3 breast cancer included in the Castellon Cancer Registry (Comunidad Valenciana, Spain) were used.

[Prospective study to evaluate diagnostic accuracy in benign anal diseases in primary care].

Objective: To analyse the diagnostic performance of the primary care (PC) doctor in benign anal diseases.

Design: Cross-sectional study including patients referred to our clinic from PC with the diagnosis of clinical conditions pertaining to benign anal diseases between 1st June and 31st December 2007. The diagnosis established by the PC doctor was compared with that of 2 medical specialists in general and digestive diseases surgery.

[Ileal pouch-anal anastomosis for Crohn's disease. Current status].

Ileal pouch-anal anastomosis has become the standard surgical procedure for the treatment of ulcerative colitis and familial polyposis of the colon. Nevertheless, its use in Crohn's disease patients remains controversial. A review was carried out in order to determine the present scientific evidence on the usefulness of ileal pouch-anal anastomosis in Crohn's disease patients.

[Diabetic mastopathy. Features in four patients].

Diabetic mastopathy is a clinicopathologic entity that represents less than 1% of benign breast disease and is mainly related to type 1 diabetes. The pathogenesis is unknown but the most convincing hypothesis postulates extracellular collagen deposit and predominantly B-cell inflammation with autoimmune response. The clinical, radiological and pathological features of four patients with diabetic mastopathy are presented.