Publications by authors named "Miguel Alanis"
Microbiol Spectr
March 2024
Article Synopsis
- A significant rise in hospital-acquired bacterial infections during the COVID-19 pandemic has prompted urgent attention to antibiotic-resistant pathogens, making the search for new antimicrobial compounds essential.
- The study focuses on the initiation factor 1 (Cd-IF1) which is crucial for protein synthesis in bacteria, presenting its NMR structure and how it interacts with the 30S ribosomal subunit, highlighting the importance of a specific α-helix for binding.
- A peptide derived from this α-helix demonstrated potent antibacterial activity, suggesting a promising direction for developing new antibiotics to combat drug-resistant bacterial infections.
