Publications by authors named "Miguel A Vences"

Article Synopsis
  • The study aimed to investigate cerebral hemodynamics and assess elevated intracranial pressure (ICP) in severe COVID-19 patients using transcranial Doppler and optic nerve sheath diameter (ONSD) measurement.
  • A retrospective cohort of 142 patients was analyzed, revealing that 83.1% had elevated ICP based on ONSD measurements, with a mortality rate of 16.2%, and factors like age and carbon dioxide levels influencing outcomes.
  • Results indicated that older age was linked to higher ONSD, while elevated carbon dioxide levels were associated with a decreased risk regarding pulsatility index, while mean velocity was identified as a mortality risk factor.
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  • The study evaluates the effectiveness and safety of the Silk Vista Baby (SVB) flow diverter for treating small cerebral aneurysms, focusing on long-term follow-up.
  • Researchers analyzed data from 50 patients treated with the SVB between September 2018 and June 2021, noting a low complication rate of 8% during procedures.
  • Results showed a 100% technical success rate, no re-ruptures, and a high occlusion rate of 94% at the 12-month follow-up, confirming the SVB as a safe and effective treatment option.
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  • The study aimed to analyze the clinical and demographic traits of patients with acute cerebral infarction in Peru and to identify risk factors for complications during hospitalization.
  • Conducted from January to September 2021, the research involved 192 patients and evaluated various health metrics using statistical models to determine risk ratios for complications.
  • Results revealed that 32.3% of patients had complications, mostly infectious (22.4%) and neurological (17.7%), with stroke severity increasing risk and higher albumin levels offering some protection.
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Background: Vaccination is an important public health strategy; however, many neurological adverse effects are associated with COVID-19 vaccination, being encephalitis a rare manifestation.

Case Presentation: We present the case of a 33-year-old woman who received the first dose of the BBIBP-CorV vaccine against COVID-19 on April 4 and the second dose on April 28, 2021. Three days after receiving the second dose, she experienced a subacute episode of headache, fever, insomnia, and transient episodes of environment disconnection.

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Background And Objectives: COVID-19-related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.

Methods: This was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 and June 2021 tested for severe acute respiratory syndrome coronavirus 2 infection.

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Background And Objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020).

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Leptomeningeal metastasis is an infrequent form of cancer expression, and it has a poor prognosis due to its torpid evolution and its challenging diagnosis. We report the case of a 68-year-old woman with rapidly progressing cognitive decline and focal epilepsy. Brain magnetic resonance imaging showed extensive gyriform hypersignal in the right precentral sulcus region, without mass effect, tenuous contrast uptake, and hydrocephalus with transependymal edema.

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Background: Many low- and middle-income countries, including Latin America, lack access to biomarkers for the diagnosis of prodromal Alzheimer's Disease (AD; mild cognitive impairment due to AD) and AD dementia. MRI visual rating scales may serve as an ancillary diagnostic tool for identifying prodromal AD or AD in Latin America. We investigated the ability of brain MRI visual rating scales to distinguish between cognitively healthy controls, prodromal AD and AD.

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We describe the case of a 72-year-old man who received the first dose of the BNT162b2 (COMIRNATY) vaccine against COVID-19 on 18 May 2021, and the second dose on 9 September 2021. One day after receiving the first dose, he cursed with malaise, headache, fever, confusion, aggressiveness, and gait alterations. We performed serum and cerebrospinal fluid (CSF) tests (finding elevated proteins in CSF) with negative results for infectious, systemic, and neoplastic causes.

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Article Synopsis
  • Recent studies showed a rise in cerebral venous thrombosis (CVT) cases during the COVID-19 pandemic, prompting this evaluation of hospitalization and mortality rates comparing the pandemic year (2020) to the year prior (2019).
  • A cross-sectional study analyzed data from 171 stroke centers worldwide, focusing on CVT admissions and associated mortality from January 2019 to May 2021, revealing no significant differences in overall CVT volume or mortality between 2019 and 2020.
  • However, the first five months of 2021 saw a notable increase in CVT admissions compared to 2019 and 2020, with higher mortality rates linked to COVID-19-positive patients and instances of vaccine-induced immune
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Objectives: COVID-19 pandemic has forced important changes in health care worldwide. Stroke care networks have been affected, especially during peak periods. We assessed the impact of the pandemic and lockdowns in stroke admissions and care in Latin America.

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Introduction: Lymphomatosis cerebri is a rare form of primary central nervous system lymphoma characterized by an atypical clinical presentation and neuroimaging, with a poor short-term prognosis.

Case Report: A 51-year-old woman began with clinical manifestations characterized by rapidly progressing cognitive impairment associated with a behavioral disorder, myoclonus, and gait disturbance. The brain magnetic resonance image showed extensive signaling in the bilateral periventricular white matter.

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Critical asthma syndrome is the most severe consequence of an acute asthma exacerbation. Allergic bronchopulmonary aspergillosis is one of the most frequent pathologies that mimic critical asthma syndrome and is associated with a high mortality risk when timely diagnosis is not achieved in difficult-to-control asthmatic patients. We present the case of a 15-year-old male who was admitted to the intensive care unit with critical asthma signs and symptoms, where a diagnosis of allergic bronchopulmonary aspergillosis was made.

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