Publications by authors named "Mieke D'Hooge"
Article Synopsis
- The study aimed to evaluate the reliability and validity of three questionnaires designed to assess dual-tasking difficulties in people with multiple sclerosis (PwMS).
- A total of 356 participants across six countries were analyzed, showing that the questionnaires had strong test-retest reliability and internal consistency, with the DIDA-Q performing the best.
- The findings indicate that these self-reported questionnaires are effective tools for measuring the impact of dual-task challenges on the daily lives of ambulatory PwMS in both research and clinical settings.
Article Synopsis
- People with progressive multiple sclerosis (PMS) often experience both motor and cognitive fatigue, affecting their ability to walk and think effectively.
- A study involving 298 PMS patients revealed that over half exhibited walking fatigability (WF), while two-thirds showed cognitive fatigability (CF), with WF linked to worse clinical outcomes and higher levels of fatigue.
- Despite both kinds of fatigue being prevalent, the extent of cognitive and walking fatigability was not strongly associated, indicating that different factors may influence them in PMS patients.
Article Synopsis
- Cognitive-motor interference (CMI) in people with multiple sclerosis (pwMS) shows varying effects based on the difficulty of tasks performed simultaneously.
- The study examined nine combinations of cognitive and walking tasks to assess how task difficulty influences performance and the cost of multitasking on gait and correct answers.
- Results indicated that while pwMS performed worse overall compared to healthy controls (HC), there was no significant difference in dual-task costs (DTC) between the two groups, highlighting the impact of task difficulty on motor performance.
Background: Dual tasking constitutes a large portion of most activities of daily living; in real-life situations, people need to not only maintain balance and mobility skills, but also perform other cognitive or motor tasks at the same time. Interest toward dual-task training (DTT) is increasing as traditional interventions may not prepare patients to adequately face the challenges of most activities of daily living. These usually involve simultaneous cognitive and motor tasks, and they often show a decline in performance.
View Article and Find Full Text PDFThe aim was to compare the effectiveness of dual-task training (DTT) compared to single mobility training (SMT) on dual-task walking, mobility and cognition, in persons with Multiple Sclerosis (pwMS). Forty pwMS were randomly assigned to the DTT or SMT groups. The DTT-group performed dual-task exercises using an interactive tablet-based application, while the SMT-group received conventional walking and balance exercises.
View Article and Find Full Text PDFBackground: Cognitive impairment affects half of the multiple sclerosis (MS) patient population and is an important contributor to patients' daily activities. Most cognitive impairment studies in MS are, however, cross-sectional or/and focused on the early disease stages.
Objective: We aim to assess the time course of decline of different cognitive domains.
Background: Information on the relative influence of cognitive and physical impairment on the quality of life in multiple sclerosis is currently limited and no scientific consensus has been reached yet.
Objective: For this reason, we wanted to examine the relative contribution of cognitive and physical impairment measures comprised in the MSFC test on quality of life in MS.
Methods: In the National MS Center Melsbroek, patients regularly undergo MSFC and EQ5D measurements.