Publications by authors named "Midori Fukumura"
Article Synopsis
- Taurine is a free β-amino acid found in high concentrations in mammalian tissues and is important for biological processes like anti-oxidation and immune responses.* -
- The study focused on how taurine affects the expression of immune-related genes in macrophage-like cells, particularly enhancing the mRNA levels of CXCR2 and CXCR4.* -
- Among taurine analogs tested, GABA notably increased CXCR4 expression, while hypotaurine had a slight effect and β-alanine had none, highlighting taurine's specific role in regulating immune gene expression.*
Effect of Taurine on Cell Function via TXNIP Induction in Caco-2 Cells.
Adv Exp Med Biol
September 2019
Taurine (2-aminoethanesulfonic acid), a sulfur-containing β-amino acid, is a free amino acid present in high concentrations in mammalian tissues. Taurine has pivotal roles in anti-oxidation, membrane stabilization, osmoregulation, anti-inflammation, and other process. In a DNA microarray analysis, we previously found that taurine markedly increases the mRNA expression of thioredoxin interacting protein (TXNIP) in Caco-2 cells.
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