Publications by authors named "Micskey E"

Objectives: The aim of the study was to evaluate the incidence, baseline disease characteristics, and disease location based on the Paris classification in pediatric inflammatory bowel disease (IBD) in the Hungarian nationwide inception cohort. In addition, 1-year follow-up with therapy was analyzed.

Methods: From January 1, 2007 to December 31, 2009, newly diagnosed pediatric patients with IBD were prospectively registered.

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Article Synopsis
  • The study evaluated the role of esophagogastroduodenoscopy (EGD) in diagnosing upper gastrointestinal (UGI) involvement in children with inflammatory bowel disease (IBD), particularly focusing on Crohn's disease (CD) and ulcerative colitis (UC).
  • During the study from 2007 to 2009, 420 children were diagnosed with IBD, with a prevalence of 63% CD and 31% UC, and EGD was performed on 56% of patients, revealing significant UGI lesions in many.
  • The findings indicated that there is a notable UGI involvement in children with both CD and UC, with one-third of CD patients showing significant lesions, but EGD provided a definitive diagnosis for
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27 long term monitored coeliac children were assessed. The average length of follow-up was 6.4 years, the average age of the children was 11.

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The authors present the cases of 4 children who suffered from saccharose-isomaltose malabsorption. The clinical symptoms developed following artificial feeding. The diagnosis was made by the histological examination of small intestine samples and with the simultaneous measurement of disaccharide enzyme activity.

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IgA and IgG type antibodies against gliadin were demonstrated in 396 serum samples of 350 patients with immunofluorescence method. The procedure was used in cases of clinically suspected celiac disease and for the control of the diet of patients with diagnosed celiac disease. The sensitivity of the patient material was 83% in the case of antibodies against IgA and 85% with antibodies against IgG.

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The authors treated 17 food allergic, 2-14 year old children with chemoprophylactic drugs. The patients got either ketotifen or DSCG in random allocated for 4 weeks and thereafter a washout period of 2 weeks separated the trial period of the other drug. Oral challenge with the food was performed before the trial period and after a 4 week lasting elimination diet on the last day of each treatment.

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The authors compared the results of mycologic examinations of asthmatic and control patient's throat. Fungi other than Candida were cultivated from the throat in 15% of asthmatic children and 3% of controls. In secrets from the lower respiratory tract gained by bronchoscopy, laryngoscopy, or through tracheostomy there were moulds in 34% among the asthmatics and in 15% of the other cases.

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