Auditory maturation in premature infants: a potential pitfall for early cochlear implantation.

Objectives/hypothesis: To describe spontaneous hearing improvement in the first years of life of a number of preterm neonates relative to cochlear implant candidacy.

Study Design: Retrospective case study.

Methods: Hearing levels of 14 preterm neonates (mean gestational age at birth = 29 weeks) referred after newborn hearing screening were evaluated.

Rett syndrome and long-term disorder profile.

In a cohort of 103 females clinically diagnosed with Rett syndrome (RTT), 91 had a detectable MECP2 mutation. Emphasis on details of natural history facilitated grouping of females with the same MECP2 mutation and the development of so-called disorder profiles. Some examples of disorder profiles of different recurrent MECP2 mutations are discussed.

Level of psychosocial adaptation in young school children with otitis media.

Objective: Assessment of the level of psychosocial adaptation in Dutch young school children with persistent and/or recurrent otitis media compared to a U.S. community sample.