Publications by authors named "Mickael Tordjman"

The central role of imaging in diagnosing disorders affecting the sacroiliac joints (SIJs) necessitates a comprehensive understanding of the advantages, limitations, and potential pitfalls of the imaging techniques that can be used. In this article, the anatomy and biomechanics of SIJs are exposed, outlining their unique features, particularly the division into anteroinferior cartilaginous and postero-superior ligamentous parts. Overall, the goal of this article is to offer a comprehensive understanding of imaging techniques, anatomic complexity, and diagnostic considerations relevant to SIJs disorders, facilitating accurate diagnosis and patient management in clinical practice and research.

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Purpose: Neurogenic heterotopic ossification (NHO) of the hip is a frequent complication of spinal cord injuries, often requiring surgical management. Pre-surgical imaging assessment is essential, usually with computed tomography (CT)-scan. We aimed to compare magnetic resonance imaging (MRI) and CT for pre-surgical imaging assessment of the NHO, particularly for their relationships with vessels and nerves.

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Article Synopsis
  • - The review discusses how integrating artificial intelligence (AI) with positron emission tomography (PET) imaging can enhance drug discovery, particularly in the field of oncology and immunotherapy.
  • - Out of 87 studies initially identified, 15 specifically focused on the application of AI and PET for drug discovery, with most studies using a combination of PET and CT images and analyzing data mostly from single institutions.
  • - Although many studies explored AI's role in prognosis and tumor phenotyping, there are concerns about the validity of their models, with a significant portion lacking rigorous validation methods. Overall, this integration could revolutionize the therapeutic development process but requires further investigation.
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While musculoskeletal imaging volumes are increasing, there is a relative shortage of subspecialized musculoskeletal radiologists to interpret the studies. Will artificial intelligence (AI) be the solution? For AI to be the solution, the wide implementation of AI-supported data acquisition methods in clinical practice requires establishing trusted and reliable results. This implementation will demand close collaboration between core AI researchers and clinical radiologists.

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The surgical decision to attempt nephron-sparing surgery (NSS) in children with renal tumors can be difficult. In adults, nephrometric tools are used for decision-making. More than 90% of low-complexity tumors are eligible for NSS, and high-complexity tumors often require total nephrectomy.

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In vivo characterization of intervertebral disc (IVD) mechanical properties and microstructure could give an insight into the onset and progression of disc pathologies. Ultrasound shearwave elastography provided promising results in children, but feasibility in adult lumbar discs, which are deep in the abdomen, was never proved. The aim of this work was to determine the feasibility and reliability of ultrasound assessment of lumbar IVD in adults.

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Purpose: Proton magnetic resonance spectroscopy (H MRS) offers biomarkers of metabolic damage after mild traumatic brain injury (mTBI), but a lack of replicability studies hampers clinical translation. In a conceptual replication study design, the results reported in four previous publications were used as the hypotheses (H1-H7), specifically: abnormalities in patients are diffuse (H1), confined to white matter (WM) (H2), comprise low N-acetyl-aspartate (NAA) levels and normal choline (Cho), creatine (Cr) and myo-inositol (mI) (H3), and correlate with clinical outcome (H4); additionally, a lack of findings in regional subcortical WM (H5) and deep gray matter (GM) structures (H6), except for higher mI in patients' putamen (H7).

Methods: 26 mTBI patients (20 female, age 36.

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Background: Pancreatic microcystic serous cystadenoma are rare benign pancreatic tumors. No treatment is needed in most cases as this lesion is often discovered incidentally. Surgery is not required except in symptomatic cases.

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Background & Aims: The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a recently described peculiar form of cholelithiasis associated with the ATP-binding-cassette subfamily B, member 4 () gene deficiency. The purpose of our study was to analyse the relationship between magnetic resonance (MR) features and the genetic status of in people with LPAC syndrome.

Methods: A total of 233 individuals with proven LPAC syndrome were enrolled between January 2003 and June 2018 in a retrospective single-centre study.

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Nannizziopsis spp., fungi responsible for emerging diseases, are rarely involved in human bone and joint infections. We present a rare case of septic arthritis with necrotizing cellulitis caused by N.

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Article Synopsis
  • Synovial sarcomas are rare cancers mostly found in young adults, and this study looked at how imaging tests could help predict how long patients might live.
  • Researchers studied 98 patients who had these tumors and found that factors like tumor size and presence of calcifications could help doctors understand patient outcomes better.
  • The study concluded that certain imaging features, especially calcifications seen in CT scans, can give important clues about a patient's long-term health beyond just age and tumor grade.
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We report the case of a 58-year-old immunocompetent man from Algeria, who presented to the hospital with fever and hepatic cytolysis. Abdominal computed tomography scan showed a homogeneous splenomegaly and a hypodense 12-mm mass on the posterior wall of the esophagus. After ruling out tuberculosis, the patient was diagnosed with brucellosis.

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Purpose: Heterotopic ossification (HO) is defined by the formation of mature lamellar bone in periarticular soft tissue due to prolonged immobility. This study aimed to explore the imaging features of HOs in immobilized COVID-19 patients compared to other causes previously described in the literature.

Method: This retrospective single centre study included patients with severe COVID-19 hospitalized in intensive care unit (ICU) with mechanical ventilation and affected by HOs between March 2020 and December 2021.

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Objectives: Vertebral invasion is a key prognostic factor and a critical aspect of surgical planning for superior sulcus tumors. This study aims to further evaluate MRI features of vertebral invasion in order to distinguish it from reactive inflammatory changes.

Methods: Between 2000 and 2016, a retrospective study was performed at a single institution.

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Purpose: Resting state functional magnetic resonance imaging (rsfMRI) is an emerging tool to explore the functional connectivity of different brain regions. We aimed to assess the disruption of functional connectivity of the Default Mode Network (DMN), Dorsal Attention Network(DAN) and Fronto-Parietal Network (FPN) in patients with glial tumors.

Methods: rsfMRI data acquired on 3T-MR of treatment-naive glioma patients prospectively recruited (2015-2019) and matched controls from the 1000 functional-connectomes-project were analyzed using the CONN functional toolbox.

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Article Synopsis
  • Many countries face challenges in widespread COVID-19 testing due to limited RT-PCR kits and CT-scans, prompting the need for a pre-test probability score for SARS-CoV-2 infection.
  • The study analyzed data from 605 patients across four university hospitals, focusing on demographic details, symptoms, and blood test results to identify key factors indicating infection risk.
  • The developed PARIS score demonstrated high accuracy in predicting SARS-CoV-2 infection, with a 93% positive predictive value and a 98% negative predictive value, making it a useful tool for clinicians in prioritizing tests and managing patient care.
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Introduction: Covid-19 pneumonia CT extent correlates well with outcome including mortality. However, CT is not widely available in many countries. This study aimed to explore the relationship between Covid-19 pneumonia CT extent and blood tests variations.

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Objectives: To evaluate the diagnostic and prognostic performance of CT in patients referred for COVID19 suspicion to a French university hospital, depending on symptoms and date of onset.

Methods: From March 1st to March 28th, 214 patients having both chest CT scan and reverse transcriptase polymerase chain reaction (RT- PCT) within 24 h were retrospectively evaluated. Sensitivity, specificity, negative and positive predictive values of first and expert readings were calculated together with inter reader agreement, with results of RT-PCR as standard of reference and according to symptoms and onset date.

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Objectives: CT-guided radiofrequency ablation (CT-RFA) is considered to be the gold standard for treatment of osteoid osteoma (OO) yet treatment failures (TFs) continue to be reported. This systematic review was conducted to evaluate factors associated with TF, such as ablation time, lesion location, and patient age as well as evaluating how TF has trended over time.

Methods: Original studies reporting on patients undergoing CT-RFA of OO published between 2002 and 2019 were identified.

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Objectives: To perform a systematic review on apparent diffusion coefficient (ADC) values of renal tumor subtypes and meta-analysis on the diagnostic performance of ADC for differentiation of localized clear cell renal cell carcinoma (ccRCC) from other renal tumor types.

Methods: Medline, Embase, and the Cochrane Library databases were searched for studies published until May 1, 2019, that reported ADC values of renal tumors. Methodological quality was evaluated.

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