Activity in Group-Housed Home Cages of Mice as a Novel Preclinical Biomarker in Oncology Studies.

Background: Improving experimental conditions in preclinical animal research is a major challenge, both scientifically and ethically. Automated digital ventilated cages (DVC) offer the advantage of continuous monitoring of animal activity in their home-cage. The potential utility of this technology remains understudied and deserves investigation in the field of oncology.