Publications by authors named "Micillo F"
Article Synopsis
- Peripheral insulin resistance (IR) is a key risk factor for various serious health conditions, including type 2 diabetes and neurodegenerative diseases.
- Research has identified the brain as a region that responds to insulin, impacting its metabolism and function, but the exact mechanisms connecting IR and brain health are still not well understood.
- The review will explore the link between insulin resistance and Alzheimer's disease, and propose potential therapeutic strategies to prevent brain IR and its associated impacts.
Family members of older incompetent patients are increasingly playing an essential role in the decision-making process relating to medical treatment. Furthermore, rights of patients and carers and the extent of their legal involvement vary widely across the European Union. Starting with an illustrative case within the Italian legal framework, this review focuses on statutory laws in the European Union to analyse the role and the rights of surrogates on behalf of older incompetent patients.
View Article and Find Full Text PDFBackground: Homozygous mutations in acid-labile subunit (IGFALS) gene result in short stature, very low circulating levels of acid-labile subunit (ALS), insulin growth factor 1 (IGF1) and insulin growth factor binding protein 3 (IGFBP3) and a poor response to growth hormone (GH). The impact of IGFALS mutations heterozygosity on growth is unknown.
Patient And Methods: We describe a 10-year-old girl with severe short stature (height -3.
Aim: To test the efficacy of a proprietary nutraceutical combination in reducing insulin resistance associated with the metabolic syndrome (MetS).
Methods: Sixty-four patients with MetS followed at a tertiary outpatient clinic were randomly assigned to receive either placebo or a proprietary nutraceutical combination (AP) consisting of berberine, policosanol and red yeast rice, in a prospective, double-blind, placebo-controlled study. Evaluations were performed at baseline and after 18 wk of treatment.
Background And Aims: Some nutraceuticals are prescribed as lipid-lowering substances. However, doubts remain about their efficacy. We evaluated the effects of a nutraceutical combination (NC), consisting of 500 mg berberine, 200mg red yeast rice and 10mg policosanols, on cholesterol levels and endothelial function in patients with hypercholesterolemia.
View Article and Find Full Text PDFUsefulness of NT-proBNP in the assessment of patients with aortic or mitral regurgitation.
J Cardiovasc Med (Hagerstown)
December 2009
Background: Recent application of brain natriuretic peptide and N-terminal prohormone brain natriuretic peptide (NT-proBNP) in cardiac valvular disease is very promising.
Aims: To test the usefulness of NT-proBNP in the assessment of patients with aortic or mitral regurgitation.
Patients And Methods: Sixty-seven patients - 23 with aortic and 12 with mitral regurgitation vs.