, , , and Polymorphisms Associated with Coenzyme Q Availability Affect the Subjective Quality of Life Score (SF-36) after Long-Term CoQ Supplementation in Women.

The single nucleotide polymorphisms (SNPs) rs3808607, rs2072183, rs2032582, and rs1761667 are associated with coenzyme Q (CoQ) bioavailability in women after long-term CoQ supplementation. However, the beneficial aspects of the association between these SNPs and CoQ supplementation remain unknown. We investigated their relationship using the subjective quality of life score SF-36 by reanalyzing previous data from 92 study participants who were receiving ubiquinol (a reduced form of CoQ) supplementation for 1 year.

, , , and Polymorphisms Are Associated with Increased Serum Coenzyme Q after Long-Term Supplementation in Women.

Coenzyme Q (CoQ), an essential component for energy production that exhibits antioxidant activity, is considered a health-supporting and antiaging supplement. However, intervention-controlled studies have provided variable results on CoQ supplementation benefits, which may be attributed to individual CoQ bioavailability differences. This study aimed to investigate the relationship between genetic polymorphisms and CoQ serum levels after long-term supplementation.

Miso Soup Consumption Enhances the Bioavailability of the Reduced Form of Supplemental Coenzyme Q.

Coenzyme Q (CoQ) is an essential compound that is involved in energy production and is a lipid-soluble antioxidant. Although it has been proposed as an antiaging and a health-supporting supplement, its low bioavailability remains a significant issue. Concurrent food intake enhances the absorption of orally administered CoQ, but it has not been fully established whether specific food substances affect intestinal CoQ absorption.