Beneficial Effects of a Formulated Supplement of Ascidiacea (Halocynthia-roretzi)-derived Plasmalogen and Tuna-derived Elastin on Memory Function in Elderly Japanese Subjects; A Randomized, Double-blind, Placebo-controlled Study.

The beneficial effects of a formulated supplement of plasmalogen and elastin on the memory function in healthy elderly subjects were investigated by a randomized, double-blind, placebo-controlled, parallel-group analysis. Plasmalogen has been shown to exert beneficial effects on cognitive function in animal models and human clinical trials, while elastin improves vascular elasticity and increases blood flow. The levels of plasmalogen and elastin decreases with aging.

Beneficial Effects of Saw Palmetto Fruit Extract on Urinary Symptoms in Japanese Female Subjects by a Multicenter, Randomized, Double-Blind, Placebo-Controlled Study.

Saw palmetto berry extract (SPE) is the most commonly consumed supplement by men with benign prostatic hyperplasia (BPH). The oral administration of SPE was previously shown to significantly attenuate urodynamic symptoms in the hyperactive bladders of female rats by increasing bladder capacity and prolonging the micturition interval. The amelioration of urodynamic symptoms by SPE may be partly attributed to its binding to muscarinic receptors in the urinary bladder and its inhibition of vanilloid receptors on afferent nerves.

Beneficial effects of a nobiletin-rich formulated supplement of Sikwasa () peel on cognitive function in elderly Japanese subjects; A multicenter, randomized, double-blind, placebo-controlled study.

Background: Nobiletin exerts beneficial effects on cognitive function in various animal models of Alzheimer's disease. The present study aimed to investigate the benefits and safety of a combination food of nobiletin-rich extract from peel for healthy elderly subjects.

Methods: The nobiletin-containing test food (Nobilex) comprised high-purity nobiletin powder combined with dried root powder of and dried lead powder of and was administered to elderly Japanese subjects once a day for 16 weeks.

[Analyzing the differences in positive thinking between the healthy elderly and the elderly with long-term care risk].

Objectives　In forthcoming preventive care, it is important to perceive that the health of the elderly is multifaceted. The purpose of the research is to analyze the difference in positive thinking between the elderly with long-term care risk and the healthy elderly, to clarify the relationship between long-term care risk and positive thinking.Methods　A postal mail survey, based on a self-administered questionnaire, was conducted in City A.