Publications by authors named "Michiya Watanabe"

Background: The efficacy of antifibrotic agents in idiopathic pulmonary fibrosis (IPF) has been demonstrated and early introduction is recommended, especially in patients with preserved performance status (PS). We aimed to determine the proportion of untreated IPF cases using real-world data and to assess the factors associated with non-intervention.

Methods: A prospective observational study using questionnaires was performed on 518 patients with interstitial lung disease (ILD) and their attending physicians who visited a clinic, general hospital, or tertiary respiratory center between December 2019 and October 2020.

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Although endoscopic sinus surgery (ESS) is beneficial in improving asthma symptoms, its impact on the lung function in patients with asthma and chronic rhinosinusitis remains unclear. We herein report a case of severe asthma with eosinophilic chronic rhinosinusitis, in which ESS substantially improved airflow limitation and concomitantly reduced fractional exhaled nitric oxide and blood eosinophil counts. ESS likely relieved airflow limitation by suppressing type 2 inflammatory pathways.

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Article Synopsis
  • This study investigates the use of a simple measure (delta SpO2 during a sit-to-stand test) to predict pulmonary function issues in patients with interstitial lung disease (ILD), an area where traditional tests are challenging to conduct in primary care.
  • Results showed a strong correlation between delta SpO2 and the diffusing capacity of the lungs for carbon monoxide, meaning delta SpO2 can effectively indicate gas exchange problems.
  • The findings suggest that measuring delta SpO2 could be a valuable, accessible tool for identifying lung function impairments in ILD patients.
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Background: Accumulating evidence shows an overabundance of Fusobacterium nucleatum in colorectal tumor tissues. However, the correlation between the absolute copy number of F. nucleatum in colorectal cancer tissues and colorectal cancer progression is unclear from previous reports.

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