Publications by authors named "Michiya Okada"
Article Synopsis
- * The experiment focused on the refolding of ribonuclease A, utilizing a specialized setup with integrated heating and cooling baths in the NMR probe.
- * Results showed that the rate of structural change had an exponential constant of 0.2-0.7 s(-1), indicating that the transition state formation in the refolding reaction was influenced by entropy.
A new titration system for studying protein-ligand interactions has been developed. In this system, the sample solution is circulated in the route formed by an access path in a split superconducting magnet to maintain a constant protein concentration during the titration experiments. A concentration-control procedure for the ligand/protein ratio is devised, and the ligand/protein ratio is well controlled by this apparatus.
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