Publications by authors named "Michito Teratani"
Aim: The aim of this study was to investigate the antitumor potential of guaiazulene-3-carboxylate derivatives against oral malignant cells.
Materials And Methods: Twelve guaiazulene-3-carboxylate derivatives were synthesized by introduction of either with alkyl group [], alkoxy group [], hydroxyl group [] or primary amine [] at the end of sidechains. Tumor-specificity (TS) was calculated by the ratio of mean 50% cytotoxic concentration (CC) against 3 human oral mesenchymal cell lines to that against 4 human oral squamous cell carcinoma (OSCC) cell lines.