Systematic retinotopic reaching error vectors in unilateral optic ataxia.

The main aim of this study is to determine the reference frame of the pointing errors that characterize patients with unilateral optic ataxia (OA). The reaching errors of seven patients with unilateral OA when pointing on a 2D matrix in peripheral vision were investigated in order to better qualify the reference frame of their deficit. Patients were asked to fixate a central target and then to point at one of 24 visual targets presented in their left or right peripheral visual fields, with their left or right hands.

Different MRI findings for normal elderly and very mild Alzheimer's disease in a community: implications for clinical practice the Tajiri Project.

To investigate magnetic resonance imaging (MRI) findings of very mild dementia, 485 participants were randomly selected in a community. Three hundred and forty participants were of Clinical Dementia Rating (CDR) 0 (healthy), 113 were of CDR 0.5 (questionable dementia), and 32 were of CDR 1 and 2 (including 20 Alzheimer's disease, AD).

Neural basis of the retrieval of people's names: evidence from brain-damaged patients and fMRI.

The aim of this study was to identify the neuroanatomical basis of the retrieval of people's names. Lesion data showed that patients with language-dominant temporal lobectomy had impairments in their ability to retrieve familiar and newly learned people's names, whereas patients with language-nondominant temporal lobectomy had difficulty retrieving newly learned people's names. Functional magnetic resonance imaging experiments revealed activations in the left temporal polar region during the retrieval of familiar and newly learned people's names, and in the right superior temporal and bilateral prefrontal cortices during the retrieval of newly learned information from face cues.