Publications by authors named "Michiko Yamaki"

Diabetes is a devastating disease that causes millions of deaths. Fermented rice bran (FRB), made by fermenting rice bran with and a mixture of lactic acid bacteria, was hypothesized to b able to improve diabetes-related symptoms. This study aimed to investigate the effects of FRB supplementation in mitigating type 2 diabetes symptoms and identifying FRB bioactive compounds.

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Article Synopsis
  • TAS2R genes are responsible for detecting bitter tastes and may help regulate the intake of bitter substances by influencing taste and digestion.
  • The study focused on the TAS2R38 gene, identifying three main genotypes (AVI/AVI, AVI/PAV, PAV/PAV) and their frequencies in a Japanese sample, showing no significant differences in dietary habits among these genotypes.
  • Additionally, no correlation was found between the TAS2R46 gene variations and body mass index or eating/drinking behaviors, highlighting unique genetic influences in different populations.
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Type-2 bitter-taste receptors (TAS2Rs) are important for the evaluation of food quality and the nutritional control in animals. Mutations in some TAS2Rs including TAS2R38 are known to increase susceptibility to various diseases. However, the involvement of TAS2Rs in cancers has not been well understood.

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