Publications by authors named "Michihiro Nishimura"
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Synopsis of recent research by authors named "Michihiro Nishimura"
- Michihiro Nishimura's recent research focuses on the activation mechanisms of class B1 G-protein-coupled receptors (GPCRs) by intracellular agonists, aiming to understand selective activation of these receptors.
- The 2023 article published in *Nature* presents findings that emphasize the role of ligand binding in triggering conformational changes in GPCRs, which subsequently activate intracellular transducers such as G proteins and β-arrestins.
- Nishimura underscores the importance of elucidating the selective activation pathways to better comprehend and mitigate the adverse effects associated with GPCR signaling.
