Background: Cytokines play an important role in chronic allergic eye disease.
Objectives: We examined how many kinds of cytokines are in giant papillae of vernal keratoconjunctivitis(VKC).
Methods: We resected giant papillae from 6 patients with VKC, and studied mRNA expression of cytokines in them with the reverse transcriptase-polymerase chain reaction(RT-PCR).
Purpose: To evaluate the anti-allergic effect of iodine in an allergic conjunctivities model.
Methods: Guinea pigs (n = 107) were administered iodine at three different concentrations in feed. Twenty Guinea pigs were passively sensitized by serum containing ovalbumin (OA) antibody, and eighteen Guinea pigs were actively sensitized by OA intraperitoneal injection.