Publications by authors named "Michiel A Ijsseldijk"
Objectives: Optimal treatment of stage IIIA (N2) non-small-cell lung cancer (NSCLC) is controversial. Guidelines advise induction therapy before surgical resection. A proportion of patients with cN0 NSCLC are postoperatively upstaged due to unsuspected N2 disease.
View Article and Find Full Text PDFBackground: The optimal treatment of stage I non-small-cell lung carcinoma is subject to debate. The aim of this study was to compare overall survival and oncologic outcomes of lobar resection (LR), sublobar resection (SR), and stereotactic body radiotherapy (SBRT).
Methods: A systematic review and meta-analysis of oncologic outcomes of propensity matched comparative and noncomparative cohort studies was performed.
Article Synopsis
- Early-stage non-small-cell lung cancer (NSCLC) treatment is debated; lobar resection is standard, but sublobar resections, which preserve lung tissue, show promising results.
- A systematic review and meta-analysis compared outcomes between lobar resections and parenchymal-sparing techniques for T1a NSCLC, analyzing data from 28 studies.
- Findings indicate no significant difference in 5-year overall survival rates between the two surgical approaches, although parenchymal-sparing surgery may present risks related to nodal upstaging in patients who could tolerate lobectomy.
Article Synopsis
- SBRT is a potentially curative treatment for early-stage NSCLC, but its survival outcomes might vary based on whether the diagnosis is clinically or biopsy-proven.
- The systematic review analyzed 43 studies, revealing that patients with biopsy-proven disease had lower 3-year overall survival and cancer-specific survival rates compared to those diagnosed clinically, although 5-year overall survival rates were similar for both groups.
- The findings underline the significance of obtaining pathological confirmation of malignancy before treating with SBRT, as this could impact patient outcomes.
Objectives: Chronic abdominal pain develops in 11-20% of patients undergoing abdominal surgery, partly owing to post-operative adhesions. In this study we evaluate results of a novel diagnostic and therapeutic approach for pain associated with adhesions.
Methods: Prospective cohort study including patients with a history of abdominal surgery referred to the outpatient clinic of a tertiary referral center for the evaluation of chronic abdominal pain.
Bony tumours of the chest wall are rare and radical surgical resection forms the cornerstone of treatment. Closure of the defect following radical resection can be challenging. We report the case of a 59-year-old woman with a large tumour of the thoracic wall, which was surgically resected with direct reconstruction using a sandwich technique with a Palacos(®) patch placed in a double-layer Marlex mesh.
View Article and Find Full Text PDFBackground: To date, no clinical decision rules for acute wrist injuries are available. In the past, clinical decision rules for the knee, ankle and spine injuries have been developed and validated. Implementation of these rules resulted in standardised clinical assessment at the emergency department and a substantial reduction of radiographic diagnostics.
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