Publications by authors named "Michida T"
Background And Study Aims: Diffuse infiltrative gastric cancer can be difficult to diagnose owing to a lack of endoscopic features in the superficial mucosa. Moreover, a forceps biopsy may not reveal a pathological diagnosis. We aimed to evaluate the diagnostic yield and safety of endoscopic mucosal resection (EMR) and 'open-lid submucosal biopsy', a technique wherein EMR followed by biopsy of the ulcer floor is performed for a pathological diagnosis.
View Article and Find Full Text PDFBackground: Patients with esophageal squamous cell carcinoma (ESCC) frequently develop synchronous head and neck squamous cell carcinoma (HNSCC). With advances in endoscopic technology and widespread screening of synchronous cancers, the detection of synchronous HNSCC and superficial ESCC (SESCC) is increasing. We aimed to evaluate the impact of preceding HNSCC treatment on synchronous SESCC.
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- * Key factors linked to bleeding included the use of antithrombotic agents, the size of the resection wound, and specimen size.
- * Direct oral anticoagulants (DOACs) were significantly associated with higher bleeding rates, indicating a need for caution in patients on these medications during postoperative recovery.
Background And Aims: Local recurrence is a significant concern in endoscopic resection of superficial nonampullary duodenal tumors (SNADTs). Our objective was to elucidate the clinical outcomes of salvage endoscopic treatment.
Methods: This retrospective study included consecutive patients who underwent endoscopic resection of SNADTs between January 2013 and December 2021.
Article Synopsis
- This study investigated the effectiveness and safety of endoscopic resection for lesions in patients with head and neck squamous cell carcinoma that developed after radiation therapy.
- A total of 43 patients with 57 lesions underwent this procedure, achieving complete resection in all cases, with manageable adverse events occurring in a minority of patients.
- The results showed good long-term outcomes, with low rates of local recurrence and high survival rates, indicating that endoscopic dissection is a safe and effective option for these patients.
Objectives: This study investigated the incidence of lymph node metastasis and long-term outcomes in patients with T1 colorectal cancer where endoscopic submucosal dissection (ESD) resulted in noncurative treatment. It is focused on those with deep submucosal invasion, a factor considered a weak predictor of lymph node metastasis in the absence of other risk factors.
Methods: This nationwide, multicenter, prospective study conducted a post-hoc analysis of 141 patients with T1 colorectal cancer ≥20 mm where ESD of the lesion resulted in noncurative outcomes, characterized by poor differentiation, deep submucosal invasion (≥1000 μm), lymphovascular invasion, high-grade tumor budding, or positive vertical margins.
Article Synopsis
- The study investigates the risk factors for strictures following endoscopic submucosal dissection (ESD) for cervical esophageal cancer and evaluates the effectiveness of steroid injections in preventing these strictures.
- Among 100 patients analyzed, key risk factors for stricture included larger tumor size, longer resection time, and greater circumferential mucosal defect, particularly in patients who did not receive steroid injections.
- Results indicated that steroid injections significantly reduced the incidence of stricture in patients with smaller mucosal defects (<3/4 and ≥1/2), but were less effective in those with larger defects (≥3/4).
Article Synopsis
- Paget's disease (PD) is a type of carcinoma characterized by abnormal cells in the epithelium, with two types: breast PD and extramammary PD (EMPD), the latter being harder for surgeons to navigate.
- An 83-year-old male underwent treatment for rough esophageal epithelium, which was found to be squamous cell carcinoma during a biopsy, leading to endoscopic submucosal dissection (ESD).
- The case highlighted challenges in identifying the tumor’s distribution and growth pattern, complicating preoperative assessments for the healthcare team.
Introduction: We investigated the factors associated with synchronous multiple early gastric cancers and determined their localization.
Methods: We analyzed 8,191 patients who underwent endoscopic submucosal dissection for early gastric cancers at 33 hospitals in Japan from November 2013 to October 2016. Background factors were compared between single-lesion (n = 7,221) and synchronous multi-lesion cases (n = 970) using univariate and multivariate analyses.
Article Synopsis
- The study evaluates the effectiveness of endoscopic submucosal dissection (ESD) as a treatment for local residual or recurrent colorectal tumors, building on previous findings that showed favorable long-term outcomes for large colorectal neoplasms.
- A multicenter prospective study involved 54 patients with local residual or recurrent tumors, where ESD successfully completed in 98.1% of cases and achieved high rates of en bloc and R0 resections.
- The results indicated that ESD is a safe and effective option for managing these challenging tumors, with no significant short-term complications and no tumor recurrences during a median follow-up of 60 months.
Background: Esophageal endoscopic submucosal dissection (ESD) is technically challenging, especially for trainees, and requires a safe training system. This study aimed to identify predictors of technical difficulty facing trainees performing esophageal ESD to establish such system.
Methods: This was a single-center retrospective study of patients with esophageal cancer who underwent ESD performed by trainees between January 2010 and August 2022.
Endoscopic submucosal dissection enables en bloc resection of large superficial colorectal neoplasms. However, it is sometimes challenging to retrieve a large resected specimen via the anus without sample fragmentation. A novel "bag-type" retrieval device has been developed to accomplish complete isolation and non-destructive delivery of oversized specimens.
View Article and Find Full Text PDFObjectives: Prediction of the risk of esophageal squamous cell carcinoma (SCC) by endoscopic findings without iodine staining, which is irritating to the esophagus, would be beneficial. In a previous retrospective study, we found that multiple foci of dilated vascular areas (MDV) of the esophageal mucosa, seen in narrow-band imaging (NBI)/blue laser imaging (BLI), are associated with iodine-unstained lesions and, thus, may be a predictor of esophageal SCC. This prospective study aimed to investigate the association between MDV and metachronous esophageal SCC.
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- The study investigates the distinctive endoscopic features of gastric neuroendocrine carcinoma (G-NEC) and correlates them with clinicopathological findings.
- It included a retrospective analysis of patients with G-NECs who underwent endoscopic or surgical treatment between 2005 and 2022, comparing findings with gastric neuroendocrine tumors (G-NETs) and common-type gastric adenocarcinomas.
- Key endoscopic findings in G-NEC patients, such as submucosal tumor-like elevation and absent microsurface patterns, were significantly more frequent compared to G-NETs and common-type gastric adenocarcinomas, suggesting these features can aid in more accurate diagnoses.
Article Synopsis
- The study focuses on the need for accurate classification of esophageal cancer treatment strategies based on specific anatomical subsites, highlighting the importance of anatomical landmarks.* -
- Researchers measured distances between various anatomical landmarks using techniques like endoscopic ultrasonography and CT scans, revealing notable differences based on individual body heights.* -
- The findings suggest that current methods of determining esophageal subsite boundaries are inconsistent, proposing modifications or the use of alternative landmarks for better anatomical classification.*
Chemoradiotherapy (CRT) and radiotherapy (RT) are treatment options for esophageal squamous cell carcinoma (ESCC), but local residual/recurrent cancer after CRT/RT is a major problem. Endoscopic resection (ER) is an effective treatment option for local residual/recurrent cancer. To ensure the efficacy of ER, complete removal of endoscopically visible lesions with cancer-free vertical margins is desired.
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