Statement Of Problem: An effective bond between a denture lining material and the denture base resin is necessary for proper function. Regarding the new technologies for manufacturing denture bases, a systematic search of the literature on this topic is lacking.
Purpose: The purpose of this systematic review and meta-analysis was to evaluate the bond strength between denture lining material and computer-aided design and computer-aided manufacturing (CAD-CAM) denture base resin (milled and 3-dimensionally printed) versus conventional denture base resin.