Publications by authors named "Michelle T Silva"
In the constant search for new pharmacological compounds, molecular hybridisation is a well-known technique whereby two or more known pharmacophoric subunits are combined to create a new "hybrid" compound. This hybrid is expected to maintain the characteristics of the original compounds whilst demonstrating improvements to their pharmacological action. Accordingly, we report here a series of molecular hybrid compounds based upon eugenol and chloramphenicol pharmacophores.
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- The study examined how different food groups and beverages affect serum uric acid (UA) levels in a sample of Brazilian civil servants aged 35-74.
- Key findings indicate that higher dairy intake lowers UA levels for both men and women, whereas high meat consumption raises UA levels specifically in women, and alcoholic beverages, especially beer, also increase UA levels in both sexes, depending on the amount consumed.
- The research highlights the importance of understanding dietary patterns as a whole and suggests that dietary influences on uric acid may differ between genders.