Publications by authors named "Michelle T Nguyen"

Objective: This study aimed to assess patients' interest in education content delivered through electronic modalities and identify trends in internet access and use among emergency department patients of various socioeconomic statuses.

Methods: A prospective, cross-sectional survey with 50 questions was completed by 241 English and Spanish-speaking patients in 2014 and repeated with 253 participants in 2019 at the University of California, Irvine Medical Center's Emergency Department (UCIMCED).

Results: Internet access increased from 83.

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  • A recent study investigated outcomes for children with cochlear implants affected by a Field Corrective Action (FCA), focusing on device failure rates and speech improvement after revisions.
  • The study included 27 pediatric patients from March 2017 to January 2020, finding that 73% of the implants failed, with a majority undergoing revision surgery.
  • Despite the high failure rate, speech recognition scores after revision surgery did not show significant improvement compared to before, indicating that the speech outcomes remained stable, potentially due to thorough monitoring and support from a specialized team.*
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People with serious mental illness (SMI) diagnoses who become pregnant are particularly vulnerable to symptom recurrence and resulting potential lack of decision-making capacity (Taylor et al. J Psychiatr Res 104:100-107, 2018; Bagadia et al. Int J Soc Psychiatry 66:792-798, 2020).

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Purpose: Pregnant individuals are routinely advised to undergo genetic carrier screening, followed by carrier screening in the reproductive partner if the patient's screen is positive. The objective of our study was to identify completion rates of and barriers to partner carrier screening or genetic testing.

Methods: We conducted a retrospective cohort study examining the completion of indicated partner genetic screening or testing at the Los Angeles General Medical Center Genetics clinic from January 1, 2017, to October 31, 2022.

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Linear probe point-of-care ultrasound (LPUS) presents a less invasive alternative for identifying intrauterine pregnancies (IUPs) compared to usual practice (transabdominal (TAUS) or transvaginal (TVUS) ultrasound). TAUS and TVUS can be invasive or produce lower-resolution images than LPUS. The purpose of this study is to determine whether a linear probe alone can identify first-trimester IUPs.

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  • - This study investigates the impact of subclassifying monochorionic twins with selective fetal growth restriction (type II) into two categories (IIa and IIb) based on specific Doppler ultrasound findings, due to their differing neonatal survival rates after laser surgery.
  • - Researchers conducted a retrospective analysis of 262 patients who underwent laser surgery for severe twin-twin transfusion syndrome from 2006 to 2021, focusing specifically on donor twins with growth restriction to compare survival outcomes between type IIa and IIb classifications.
  • - The analysis revealed that of the 919 patients in total, 189 had donor fetal growth restriction type II, highlighting the need to understand the associated risks for more tailored treatments and better outcomes in neonatal care
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Classically, pre-eclampsia and eclampsia are considered hypertensive disorders of pregnancy, and current diagnostic criteria include hypertension with proteinuria or other laboratory abnormalities or symptoms suggestive of end-organ damage. However, atypical presentations can occur in the absence of elevated blood pressures. We present the case of a pregnant patient who developed status epilepticus at 24 weeks and 4 days of gestation, followed by altered mental status and severely elevated transaminases.

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Objective: In 2011, School of Medicine, University of California, Irvine was among the first schools to implement a 4-year ultrasound curriculum. We aimed to find the point-of-care ultrasound (POCUS) utilization pattern among University of California, Irvine alumni.

Methods: We surveyed University of California, Irvine alumni from the class of 2011 and beyond.

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Despite evidence-based recommendations from the American College of Obstetricians and Gynecologists and the American College of Medical Genetics to offer prenatal genetic carrier screening for reproductive partners, partner carrier screening or genetic testing is inconsistently covered by pregnant patients' health insurance plans. Health policies that exclude reproductive partners from insurance coverage for prenatal carrier screening or genetic testing contradict multiple ethical principles and can even contribute to adverse maternal-child health outcomes. Incomplete or missing information regarding partner carrier status can lead to costly, invasive, and potentially risky interventions for the pregnant patient that can be avoided by a simple and less expensive blood test in the reproductive partner.

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  • Eosinophilic mastitis is a rare type of mastitis, with limited documented cases.
  • A 48-year-old woman showed signs of this condition when her right breast developed asymmetry, but no issues were found in initial imaging tests.
  • A biopsy guided by tomosynthesis was carried out to confirm the diagnosis, highlighting the importance of recognizing this rare condition for better future treatment and management.
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Radiology is not well-represented within medical school curricula, especially during the early preclinical years. It can be difficult for medical students, especially first-year medical students, to explore their interest in the field due to the lack of exposure to radiology. This article aims to highlight some of the ways that medical students can explore their interest in the field of radiology.

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Introduction: Critically injured children and teens often present to adult trauma centers or nontrauma facilities prior to transfer to a pediatric trauma center. For pediatric patients wanting transfer to the intensive care unit (ICU), there is little data to guide which can be safely transferred directly to the unit, and which should be evaluated first in the trauma bay.

Methods: We used our institutional trauma registry to evaluate transferred trauma patients over a three year period.

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The linguine sign is a radiologic sign seen on magnetic resonance imaging (MRI) that indicates intracapsular rupture of silicone breast implants. It refers to multiple curvilinear lines that appear on MRI, representing the outline of the elastomeric shell of the silicone implant floating freely within the silicone gel. The term first appeared in literature in 1992 when optimal imaging techniques and modalities for implant rupture were still unclear, and since then the term "linguine sign" has been widely used to describe evidence of intracapsular rupture.

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Macrosomia results from abnormal fetal growth and can lead to serious consequences for the mother and fetus. In cases of suspected macrosomia, patients must be counseled carefully regarding a delivery plan, and Cesarean section should be considered when indicated. Techniques to assess for suspected macrosomia include clinical measurements, ultrasound, and MRI.

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Solid pseudopapillary tumors are rare, with the majority of described cases originating in the pancreas. To date, there are only 10 documented reports of primary ovarian solid pseudopapillary tumors. Here, we describe the case of a 24-year-old woman who presented with worsening pelvic pain and dysmenorrhea.

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 The Maternal-Fetal Medicine Units (MFMU) Network developed a prediction model for calculating the likelihood of successful vaginal birth after cesarean (VBAC) in patients undergoing a trial of labor after cesarean (TOLAC). In this prediction model, Latina ethnicity is considered a negative predictive factor for successful VBAC. Subsequent studies have found mixed results regarding VBAC success in Latina ethnicity.

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The preparation of 16 oxazole- or thiazole-containing amino esters bearing a wide array of N-substitution is reported. These were accessed in 40-92% yield via an AgClO-promoted substitution reaction between a primary amine and a chloromethyl-functionalized thiazole or oxazole. These new synthetic building blocks will be useful for the preparation of new cyclopeptide analogues bearing heterocyclic backbone modifications.

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We herein report a high-resolution nanopatterning method using low voltage electromechanical spinning with a rotating collector to obtain aligned graphitized micro and nanowires for carbon nanomanufacturing. A small wire diameter and a small inter-wire spacing were obtained by controlling the electric field, the spinneret-to-collector distance, the pyrolysis parameters, the linear speed of the spinneret, the rotational speed of the collector. Using a simple scaling analysis, we show how the straightness and the diameter of the wires can be controlled by the electric field and the distance of the spinneret to the collector.

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  • Streptococcus pasteurianus is a rare pathogen that has been linked to only a few cases of neonatal infection in the past decade, with symptoms often presenting as meningitis; however, this case report highlights two unusual instances of neonatal infections manifesting in rare forms: endocarditis and pneumonitis.* -
  • The first patient experienced respiratory distress and was initially treated for sepsis; after being diagnosed with S. pasteurianus, he was given an extended course of cefepime due to complications of endocarditis, ultimately leading to his improvement.* -
  • The second patient also presented with respiratory distress and went into septic shock; similar to the first case, he was treated with antibiotics after blood cultures
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In this study, we sought to determine the accuracy of several critical care risk scores for predicting survival of Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Profile 1 patients after continuous-flow left ventricular assist device (CF-LVAD) placement. We retrospectively analyzed the records of 605 patients who underwent CF-LVAD implantation between 2003 and 2016. We calculated the preoperative HeartMate II Risk Score (HMRS) and preoperative Right Ventricular Failure Risk Score (RVFRS) and the following risk scores for postoperative days 1-5: HMRS, RVFRS, Model for End-stage Liver Disease (MELD), MELD-eXcluding International Normalized Ratio, Post Cardiac Surgery (POCAS) risk score, Sequential Organ Failure Assessment (SOFA) risk score, and Acute Physiology and Chronic Health Evaluation III.

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In obstetric practice, each pregnant woman presents with a composite of maternal and fetal characteristics that can alter the risk of significant harm without cesarean intervention. The hospital's availability of resources and the obstetrician's training, experience, and skill level can also alter the risk of significant harm without cesarean intervention. This paper proposes a clinical ethical framework that takes these clinical and organizational factors into account, to promote a deliberative rather than simplistic approach to decision-making and counseling about cesarean delivery.

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Study Objective: To demonstrate the feasibility of robotic single-site resection of advanced endometriosis using new technology.

Design: We show a video that demonstrates our technique for accomplishing single-site laparoscopic resection of advanced endometriosis. The video is a step-by-step explanation of robotic single-site resection of endometriosis nodules overlying the ureter and rectum.

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