Publications by authors named "Michelle T Chan"

Article Synopsis
  • Pancreatic adenocarcinoma is a deadly cancer that remains largely understudied, with hyperinsulinemia—linked to obesity and type 2 diabetes—identified as a potential risk factor.
  • Researchers investigated how different insulin doses affect proliferation and survival in three pancreatic cell models that represent different cancer progression stages.
  • The results showed that while insulin promotes cell survival and proliferation in certain cancer cells, its effects vary significantly across different cell types, with distinct reliance on specific signaling pathways for survival.
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