Publications by authors named "Michelle Stemler"
Article Synopsis
- The study focuses on the reactivation and dissemination of viruses in vulnerable patient populations, such as those with cancer or undergoing immunosuppressive therapy.
- A new assay combining PCR and mass spectrometry was developed to accurately and simultaneously identify multiple viruses directly from plasma samples.
- The assay showed high sensitivity and specificity, detecting additional viral infections not previously identified by standard tests, thus enhancing diagnostic capabilities in clinical settings.
The biosynthetic pathway governing inhibin heterodimer (alpha/beta) and activin homodimer (beta/beta) assembly and secretion from ovarian granulosa cells is not fully understood. Here, we examined the role of inhibin subunit glycosylation in the assembly and secretion of mature inhibin A and activin A. Inhibition of subunit glycosylation by tunicamycin treatment of alpha- and beta(A)-expressing CHO cell lines reduced inhibin but not activin secretion.
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