SPARK regulates AGC kinases central to the asexual cycle.

Apicomplexan parasites balance proliferation, persistence, and spread in their metazoan hosts. AGC kinases, such as PKG, PKA, and the PDK1 ortholog SPARK, integrate environmental signals to toggle parasites between replicative and motile life stages. Recent studies have cataloged pathways downstream of apicomplexan PKG and PKA; however, less is known about the global integration of AGC kinase signaling cascades.

SPARK regulates AGC kinases central to the asexual cycle.

Apicomplexan parasites balance proliferation, persistence, and spread in their metazoan hosts. AGC kinases, such as PKG, PKA, and the PDK1 ortholog SPARK, integrate environmental signals to toggle parasites between replicative and motile life stages. Recent studies have cataloged pathways downstream of apicomplexan PKG and PKA; however, less is known about the global integration of AGC kinase signaling cascades.

Functionally uncoupled transcription-translation in Bacillus subtilis.

Tight coupling of transcription and translation is considered a defining feature of bacterial gene expression. The pioneering ribosome can both physically associate and kinetically coordinate with RNA polymerase (RNAP), forming a signal-integration hub for co-transcriptional regulation that includes translation-based attenuation and RNA quality control. However, it remains unclear whether transcription-translation coupling-together with its broad functional consequences-is indeed a fundamental characteristic of bacteria other than Escherichia coli.

A second RNA-binding protein is essential for ethanol tolerance provided by the bacterial OLE ribonucleoprotein complex.

OLE (ornate, large, extremophilic) RNAs comprise a class of structured noncoding RNAs (ncRNAs) found in many extremophilic bacteria species. OLE RNAs constitute one of the longest and most widespread bacterial ncRNA classes whose major biochemical function remains unknown. In the Gram-positive alkaliphile , OLE RNA is abundant, and localizes to the cell membrane by association with the transmembrane OLE-associated protein called OapA (formerly OAP).

Examining the impact of modality and learning style preferences on recall of psychiatric nursing and pharmacology terms.

The purpose of this experimental research study was to explore how modality and learning style preferences impact non-prescribing, first-year Licensed Vocational Nurse (LVN) students' recall of vocabulary. Independent t-test results indicated a statistically significant mean difference in short-term recall of pharmacological and psychiatric terms, with learners receiving visual text instruction recalling significantly more vocabulary than learners receiving audio text instruction. A correlation was not found between learning preferences and vocabulary recall.

Spelling patterns in preadolescents with atypical language skills: phonological, morphological, and orthographic factors.

Several investigations have considered the spelling abilities of children with reading disability; however, the spelling patterns of children with a language learning disability (LLD) have been largely ignored. This study examined the spelling error patterns of three groups of children who met strict inclusion criteria-those with a known LLD (n = 8), chronological-age-matched peers (CA; n = 8), and a younger spelling-age-matched group (SA; n = 8). An experimental spelling measure was specially designed and administered to elucidate the underlying linguistic features (clusters, digraphs, etc.