Publications by authors named "Michelle L Bordas"
NPJ Precis Oncol
October 2019
Article Synopsis
- The study investigates how triple-negative breast cancer (TNBC) cells interact with the brain's microenvironment, specifically focusing on the role of ANGPTL4 in promoting brain metastasis.
- ANGPTL4 expression in TNBC cells is induced by astrocyte-conditioned medium (ACM) and is linked to the signaling pathways involving TGF-β2 produced by astrocytes.
- Targeting ANGPTL4 could potentially serve as a therapeutic strategy for treating brain metastases in breast cancer patients.
