Larval zebrafish possess a number of molecular and genetic advantages for rigorous biological analyses of learning and memory. These advantages have motivated the search for novel forms of memory in these animals that can be exploited for understanding the cellular and molecular bases of vertebrate memory formation and consolidation. Here, we report a new form of behavioral sensitization in zebrafish larvae that is elicited by an aversive chemical stimulus [allyl isothiocyanate (AITC)] and that persists for ≥30 min.
View Article and Find Full Text PDFThe purpose of this study was to investigate the effects of latanoprost, an ocular hypotensive prostaglandin analog, on scleral collagen fibers and laminar pores in myopic guinea pigs. Young guinea pigs underwent monocular form deprivation (FD; white plastic diffusers) from 14-days of age for 10-weeks. After the first week, FD eyes also received daily topical A) latanoprost (Lat, 0.
View Article and Find Full Text PDFGPR55, an atypical cannabinoid receptor activated by lysophosphatidylinositol (LPI) has been involved in various physiological and pathological processes. We examined the effect of GPR55 activation on rat brain microvascular endothelial cells (RBMVEC), an essential component of the blood-brain barrier (BBB). GPR55 was detected in RBMVEC by western blot and immunocytochemistry.
View Article and Find Full Text PDFEnviron Sci Process Impacts
December 2015
Passive air samplers (PASs) are simple, versatile devices that are increasingly used to determine the concentrations of semivolatile organic compounds (SVOCs) in the atmosphere. Using PAS and interpreting PAS-derived data with confidence requires a detailed understanding of the factors that control the uptake kinetics. A number of experiments were aimed at clarifying the role that the housing has in limiting the uptake of SVOCs in a PAS.
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