Publications by authors named "Michelle Hartzell"
Article Synopsis
- - Addison's disease is a rare autoimmune disorder that results in the destruction of the adrenal gland and can coexist with other autoimmune diseases, leading to a condition known as autoimmune polyendocrine syndrome type II, found in 1.4-4.5 out of 100,000 people.
- - A clinical case highlighted involved a patient experiencing severe low blood pressure that didn't improve with fluid treatment, eventually diagnosed as autoimmune polyendocrine syndrome type II.
- - The key takeaway is that primary adrenal insufficiency can cause shock that is resistant to treatment, and having one autoimmune condition raises the risk of additional autoimmune diseases.
The incidence and mortality of squamous cell carcinoma of the anus (SCCA) is on the rise, which highlights the unmet need for advances in treatment options. The landscape of treatment for this cancer is rapidly evolving with novel combination strategies including immunotherapy, radiation therapy and biomarker-guided therapy. This review article features an overview of recent advancements in both locoregional and metastatic SCCA.
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