Effects of donation frequency on U.S. source plasma donor health.

Background: Plasma-derived medicinal products (PDMPs) are essential, life-saving medicines manufactured from plasma donated by healthy human volunteers. PDMPs are used to treat a range of rare, serious, and chronic conditions, often genetic in origin. Approximately 70% of the Source Plasma (SP) used for PDMP manufacturing comes from United States (US).

Why do US source plasma donors stop donating?

Background: In the United States, source plasma (SP) donors can donate up to 104 times per year. Considering the global need for SP and plasma-derived medicinal products, it is critical to maintain the health of frequent donors. This study explores SP donors' self-reported reasons for a lapse in donating.

Plasmavigilance-Adverse events among US Source plasma donors.

Background: Source plasma (SP) is the primary starting material for 87% of plasma-derived medicinal products globally. Plasmavigilance is a program designed to collect, analyze, and monitor donor adverse events (AEs) across the SP collection industry. Donor retention depends on donors having a safe and satisfactory experience.

Impact of vehicular strike on particulate matter air quality: results from a natural intervention study in Kathmandu valley.

In this natural intervention study, we evaluated the impact of vehicular shutdown during bandhas (general strikes) and meteorological parameters on ambient PM10 concentrations (particulate matter of aerodynamic diameter 10 μm or less) in the Kathmandu Valley, Nepal. Publicly available PM10 data (January 2003-February 2008) collected at six monitoring stations were combined with meteorological and bandh data. Linear mixed effects regression models were used to examine the effects of bandhas on PM10 concentrations.